2012, Number 1
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Rev Cub Med Int Emerg 2012; 11 (1)
Prognostic value of the lactic acid in the acute pancreatitis
Soto CO, García GA, Hernández TA, Illodo HOL, Hernández HI
Language: Spanish
References: 25
Page: 2324-2333
PDF size: 224.40 Kb.
ABSTRACT
Introduction: The acute pancreatitis is severe in the 20-30 % and could be associated with a mortality between 30-45 %. Some laboratories parameters have been used as markers of tissue ischemia where the more reliable are the determinations of lactic acid and the base deficit.
Objectives: To assess the correspondence among the level of lactic acid and the evolution of patients diagnosed with acute pancreatitis.
Methods: A prospective, longitudinal, analytical and observational study was conducted in the intensive care of the “Dr. Carlos J. Finlay” Military Hospital from October, 2009 to October, 2011.
Results: Forty patients were admitted diagnosed with acute pancreatitis in the study period. The mean age was of 48,7 years. Mortality was higher in the patients aged over 55. The was predominance of male sex and mortality also was higher. The more frequent complications were the hydroelectrolytic unbalances y acid-base and the syndrome of the systemic inflammatory response.
Conclusions: There was a direct relation among the values of lactate and the appearance of systemic and local complications.
REFERENCES
Liux X, Liu Q, Pan C Barly. Preventive treatment for severe acute Pancreatitis combined with lung injury. Chin J Traumatol. 2002; 5: 190-2.
Dervenis C, Bassi C. Evidence–Based assessment of severity and management of acute pancreatitis. Br J Surg. 2000; 87: 267-8.
Karne R, Girelick H. Pancreatitis aguda. Rev Valen Patol. 2002; 21(1):35-9.
Banks PA. Practice Guidelines in Acute Pancreatitis. Am J Gastroenterol. 1997; 92:377-86.
Montejo JC, García de Lorenzo A, Ortiz LC, Bonet A. Manual de Medicina Intensiva. 2da Ed. Bogotá, Editorial Harcourt, 2001.452-6.
Pérez RR, Rodríguez PJM, Otero CM, Gil MLF, García NME, Martínez GF, Brizuela QRA. Evaluación de factores Pronósticos y Evaluación en la Pancreatitis Aguda. Rev Cub Med Militar. 2006: 35 (1).2-4.
Sánchez-Lozada R, y cols. Utilidad del déficit de base como factor pronóstico en la pancreatitis aguda. Gac Méd Méx. 2003 Vol. 139 No. 2.
Bradley El. 3rd. A Clinically based classification system for acute Pancreatitis. Summary of the international symposium on Acute Pancreatitis. Atlanta. September 11 through 18, 1992. Arah Surg. 1993; 128:586-90.
Mizock BA. Lactic acidosis. Dis Mon. 1989; 35:233-300.
Caridad Soler Morejón: Rev Cubana Med 2000;39(2):115-9
Vincent JL, Dufaye, P Berre J, et al. Serial lactate determinations during circulatory shock. Crit Care Med. 1983;11:449-51.
Dabrowski GP, Steinberg SM, Ferrara JJ, Flint LM. Valoración crítica de los puntos terminales de la reanimación del estado de choque. Surg Clin North Am 2000; 80; 847-68.
Davis JW, Schackfor SR, Holbrook TL. Base deficit as sensitive indicator of compensated shock and tissue oxygen utilization. Surg Gynecol Obstet 1991; 173; 473-76.
Nguyen B, Rivers E, Knoblich B, et al. Early lactate clearance is associated with improved outcome in severe sepsis and septic shock. Crit Care Med. 2004; 32: 1637-42.
Maravi Poma E. Recomendaciones de la 7ma Conferencia de la SEMICYCU. Pancreatitis Aguda Grave en Medicina Intensiva. Med Intensiva. 2005; 29(5): 279-304.
De Bolla A, Obeid M. Mortality in acute pancreatitis. Am R Coll Surg. Engl. 1984; 66: 184-6.
Zhang X, Dijiong W, Jiang X. ICAM-1 and Acute Pancreatitis complicated by acute lung injury. JOP 2009; 10: 8-14.
Frossard JL, Steer M, Pastor C. Acute pancreatitis. Lancet 2008; 371: 143-52.
González León CA. Comportamiento de la pancreatitis aguda en Terapia Intensiva durante el decenio 1993-2003. Rev Cubana Med 2004; 43(1).
Coca MJL, García GA, Delgado SE, Gutiérrez GL, León RM, Santamaría FSJ, Llano MY. Caracterización de la pancreatitis aguda en la unidad de cuidados intensivos. Hospital “Dr. Carlos J. Finlay”. Período de enero 2004 a enero 2006. Rev Cub Med Int Emerg 2008; 7(2): 1140-6.
Michele Sánchez Roa. Pancreatitis Aguda. Rev Medicina Interna y Medicina Crítica. Mayo 2004:1(01). Disponible en: www.medicrit.com (revisado 10/01/08)
Martínez Reina A. Clasificación Mediante GRD de pacientes diagnosticados de Pancreatitis. Med Intensiva. 2003; 27: 77-9.
Guzman TF, Miranda LE. Evaluación e importancia del ácido láctico peritoneal en pacientes con abdomen quirúrgico y su relación con la escala pronóstica apache II. Med Crit Venez. 1999; 14:31.
Whitcomb D. Acute pancreatitis. N Engl J Med 2006; 354:2142-50.
Law NM, Freeman ML. Emergency Complications of Acute and Chronic Pancreatitis. Gastroenterology Clinics of North América 2003; 32: 1169-94.