2014, Number 4
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Med Int Mex 2014; 30 (4)
Coinfection with Virus of Hepatitis B or C in Patients Infected by HIV
Segoviano-Mendoza G, Torres-Erazo DS, Tovar-Serrano A
Language: Spanish
References: 15
Page: 365-372
PDF size: 458.57 Kb.
ABSTRACT
Background: Hepatitis B and C virus (HBV/HCV) infection in HIVinfected
individuals may escape at the immune control and generate
chronic illness sometimes hidden.
Objective: To determine the existence of HIV co-infection with HBV or
HCV, in patients treated at a private hospital in Mexico City.
Material and method: A cross-sectional study performed from October
2009 to June 2012 included all patients with HIV treated at infectology
service of Sanatorium Durango Hospital Center, Mexico City. Were
ordered: transaminases, serology for hepatitis A (HAV), HBV and HCV
virus, viral loads of hepatitis B, C, HIV and CD4 count. The analysis
was performed using SPSS 13.0.
Results: 41 patients were included, 90% (
n = 37) were male and 82%
(
n = 34) were under HAART at the beginning of the evaluation; 32
attended the studies performed; 27 carried out HBV viral load, HCV
and HIV, and 29 were submitted to viral hepatitis serology, finding that
all had IgG against HAV. Nine patients showed antibodies against the
surface antigen (31%) and one had anti-HCV antibodies (3.4%). Viral
loads showed only one patient with detectable viremia of HBV and
three with detectable viral load of HCV.
Conclusions: Patients living with HIV/AIDS, even though they are on
antiretroviral treatment and adequate CD4 count and HIV viral load
undetectable, may have active co-infection with HBV and even hidden
and/or HCV, by emphasizing the importance of monitoring of that
co-infection.
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