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ISSN 2070-8718 (Print)

2010, Number 1

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Rev Cub Gen 2010; 4 (1)

Histidinemia and language disorders: case study and controls in a sample of the Cuban population

Robaina JZ, Bosch GD, Contreras RJ, Moreno AJA, Texidor LL, López BM, Morales PE, Fuentes SLE

Language: Spanish
References: 10
Page: 29-31
PDF size: 206.41 Kb.


ABSTRACT

Histidinemia is one of the most frequent innate errors during childhood with a prevalence of nearly 1:15 000, speech disorder being its more remarkable result. An analytical study of cases was carried out to twenty children with language disorders due to unknown cause, while the control group was formed by 50 children without language alterations. In both groups the concentration of histidine in serum was determined by the fluorometric spectrometry and ultramicroanalytic methods. Both procedures showed that the probability of finding high levels of histidine in an individual with isolated language disorders of unknown cause was thirty times higher than the one observed in the control group. The second method also demonstrated being a useful tool for the determination of histidine levels in serum.


REFERENCES

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