2014, Number 4
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Acta Pediatr Mex 2014; 35 (4)
Alterations of growth and nutritional status in HIV-infected pediatric patients
López-Mejía L, Bautista-Silva M, Pinzón-Navarro A, Xochihua-Díaz L
Language: Spanish
References: 32
Page: 267-279
PDF size: 716.88 Kb.
ABSTRACT
Background: Childhood is the most important period of physical growth
and cognitive development. Studies show that growth and nutritional
status of pediatric patients infected with HIV are often altered.
Objective: To evaluate the prevalence in alterations of growth and
nutritional status of HIV-infected pediatric patients treated at the HIV
Clinic of the Instituto Nacional de Pediatría in México City.
Materials and Methods: It was an observational, descriptive, transversal
study. The final sample included 49 patients, 22 girls and 27 boys
between 3 months and 18 years old. All participants underwent a complete
nutritional assessment that included anthropometric, biochemical,
clinical and dietary indicators.
Results: The most common nutritional disorder was stunting. A higher
prevalence of acute malnutrition was observed in infants, preschoolers
and hospitalized patients. The biochemical evaluation assessed the
presence of dyslipidemia and anemia. The 46.9% of the sample showed
abnormal plasma levels of triglycerides, total cholesterol, or both. On
clinical examination diarrhea was the most frequent symptom, which
was observed in 100% of hospitalized patients. The dietary assessment
showed that none of the patients followed the healthy diet baselines.
Conclusions: This study demonstrates the importance of nutritional
intervention in patients with HIV. The HIV Clinic of Instituto Nacional
de Pediatría should consider including a nutritionist as part of the
multidisciplinary team.
REFERENCES
Sociedad Andaluza de Enfermedades Infecciosas. La infección por VIH: Guía Práctica. 2o edición. España: Sociedad Andaluza de Enfermedades Infecciosas; 2003.
Lamotte J. Infección y enfermedad por VIH/SIDA. Medi San 2004;8(4):49-63.
ONUSIDA. UNAIDS Report on the global AIDS epidemic. ONU;2010.
Kathleen L, Escott-Stump S. Krause Dietoterapia. 12 edición. España: Elsevier Masson;2009.
Morales AJ, Sánchez SM, Linares S, Nandí L, Villalobos A, Cashat C, et al. Condición nutricia y apoyo alimentario en niños con VIH. Bol Med Hosp Infant Mex 2002;59:250-64.
Irlam JH, Siegfried N, Visser ME, Rollins NC. Micronutrient supplementation for children with HIV infection. Cochrane Database of Systematic Reviews 2013, Issue 10. Art. No.: CD010666.
Johann-Liang R, O’Neill L, Cervia J, Haller I, Giunta Y, Licholai T, Noel GJ. Energy balance, viral burden, insulin-like growth factor-1, interleukin-6 and growth impairment in children infected with human immunodeficiency virus. AIDS 2000;14(6):683-90.
Vania L, Santos M, Nolasco M, Ancona F, Azevedo A. Evolution of nutritional status of infants infected with the human immunodeficiency virus. Sao Paulo Med J 2000;118(5):148- 53.
Villalobos D, Maury-Sintjago E, Ríos P, Fernández C, García D, Bravo A. Evaluación del estado nutricional en pacientes pediátricos institucionalizados con VIH/SIDA. Pediatr Asunción 2011;38(1):31-39.
Shet A, Mehta S, Rajagopalan N, Dinakar C, Ramesh E, Kurpad A. Anemia and growth failure among HIV-infected children in India: a retrospective analysis. BMC Pediatrics 2009;(9):37-45.
Duggan C. Micronutrients and Child Health: Studies in International Nutrition and HIV Infection. Nut Reviews 2001;59(11):358-69.
Vigano P, Berchielli J, Hjertquist T, Vidal B, García R, Pontes J. Nutritional status and lipid profile of HIV-positive children and adolescents using antiretroviral therapy. Clin Sci 2011;66(6):997-1002.
Delphine J, Lévine M, Ortega-Rodríguez E, Eaye A, Polak M, Vilmer E, Levy C. Clinical and metabolic presentation of the lipodystrophic syndrome in HIV-infected children. AIDS 2000;14:2123-28.
Sánchez N. El síndrome de lipodistrofia y su relación con pacientes con VIH/SIDA y la terapia antirretroviral. Ciencias 2008;25(2):47-65.
Rabkin M, El-Sadr W, Abrams E. Manual Clínico Pediátrico. 1° ed. Nueva York: Columbia; 2004.
Mehta M, Corkins R, Lyman B, et al. Defining Pediatric Malnutrition: A Paradigm Shift Toward Etiology-Related Definitions. JPEN J Parenter Enteral Nutr. Published online 25 March 2013.
Suverza A, Haua K. El ABCD de la evaluación del estado de nutrición. 1ºedición. México: Mc Graw Hill;2010.
World Health Organization. Concentraciones de hemoglobina para diagnosticar la anemia y evaluar su gravedad. WHO. 2011. (WHO/NMH/NHD/MNM/11.1)
Venkatesh K, Luriel M, Triche E, Bruyn G, Harwell J, Mc- Garvey S, Gray G. Growth of infants born to HIV-infected women in South Africa according to maternal and infant characteristics. Trop Med Int Health. 2010;15(11):1364-74.
Fields-Garner C. Compendio de Conocimientos Sobre la Infección por el VIH y Temas Relacionados con Nutrición. WISHH 2006;1-47.
Arpadi S. Growth Failure in Children with HIV infection. JAIDS 2000;25(1):37-42.
Gibb DM, Duong T, Tookey PA, Sharland M, TudorWilliams G, Novelli V, et al. Decline in mortality, AIDS and hospital admissions in perinatally HIV-1 infected children inthe United Kingdom and Ireland. BMJ 2003;327(7422):1019.
Banjoko S, Oseni F, Togun R. Iron status in HIV-1 infection: implications in disease pathology. BMC Clinical Pathology 2012;12:26.
Bergersen BM, Sandvik L, Bruun JN, Tonstad S. Elevated Framingham risk score in HIV-positive patients on highly active antiretroviral therapy: results from a Norwegian study of 721 subjects. Eur J Clin Microbiol Infect Dis 2004;23:625-30.
Nekhai S, Kumari N, Dhawan S. Role of cellular iron and oxygen in the regulation of HIV-1infection. Future Virol 2013;8(3):301–311.
Hall V. Síndrome de Inmunodeficiencia Adquirida-Terapia Antirretroviral. Costa Rica: CIMED; 2003.
Gutiérrez S, De León M, Cuñetti L, Gutiérrez G, Giménez V, Quian J. Dislipemia y lipodistrofia en niños uruguayos VIH positivos en tratamiento antirretroviral. Rev Méd Urug 2006;22(3):197-202.
López P, Caicedo Y, Rubiano LC, Cortés CA, Valencia A, Ramírez O, et al. Alteraciones metabólicas con terapia antirretroviral altamente efectiva en niños positivos para VIH, Cali, Colombia. Infect 2009;13(4):283-92.
Miller T, Somarriba G, Kinnamon D, Weinberg G, Friedman L, Scott G. The Effect of a Structured Exercise Program on Nutrition and Fitness Outcomes in Human Immunodeficiency Virus-Infected Children. AIDS Res Hum Retroviruses 2010;26(3):313-18.
Calza L, Manfredi R, Chiodo F. Hyperlipidaemia in patients with HIV-1 infection receiving highly active antiretroviral therapy: Epidemiology, pathogenesis, clinical course and management. Int J Antimicrob Agents 2003;22:89-99.
NOM-037-SSA2-2002, Para la prevención, tratamiento y control de las dislipidemias.
Rodríguez-Carranza SI, Aguilar-Salinas C. Anormalidades metabólicas en pacientes con infección por VIH. Rev invest clín 2004;56(2):193-208.