Haro-Acosta ME, Esparza-Cisneros JR, Delgado-Valdez JH, Ayala-Figueroa RI

Language: Spanish
References: 30
Page: 398-403
PDF size: 189.94 Kb.

ABSTRACT

Background: C-reactive protein (CRP) is a nonspecifi c marker of infl ammation with low serum levels, which are not usually detectable. In order to assess cardiovascular risk in adults apparently healthy, ultrasensitive methods are used, and the CRP measured through these techniques is known as ultrasensitive C-reactive protein (US-CRP). Some researchers report an association of US-CRP with some anthropometric parameters in children with no apparent disease. The aim was to associate US-CRP with nutritional status and biochemical profi les in Mexican schoolchildren.
Methods: In this cross-sectional study 300 healthy children (aged 10 to 12 years) were evaluated. Weight, height, body mass index (BMI), waist circumference, body fat percentage, glucose, lipid profi les and US-CRP were measured. Exclusion criteria was: US-CRP > 10mg/L. We used multivariate regression models.
Results: 53.7 % were girls and 46.3 % were boys. The US-CRP median was of 0.3 mg/L (range: 0.3 mg/L-6.8 mg/L), and it was positively and significantly correlated with BMI (β = 0.226, p = 0.032) and LDL-C (β = –0.267, p = 0.007) and negatively associated with cholesterol (β = –0.267, p = 0.007).
Conclusion: There is an association between US-CRP and cardiovascular risk indicators, such as obesity and some lipid disorder in childhood; therefore, US-CRP may be used for close examination in Mexican children.

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