2014, Number 609
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Rev Med Cos Cen 2014; 71 (609)
Consideraciones generales de la radioterápia en los tumores cerebrales pediátricos
Rodríguez RC, Orozco CA, Liu WYC
Language: Spanish
References: 33
Page: 165-171
PDF size: 179.18 Kb.
ABSTRACT
Brain tumors are the second
most common cancer and
the leading cause of death
according to the surveillance,
epidemiology and survival
in this population per year,
with a slight predominance
in males. Brain tumors are
classified according to their
histological types. The 40 % are
infratentorial, supratentorial,
54% and 6% are located
in the medulla. Diagnosis
is made with CT and MRI
and treatment primarily
is surgery or radiotherapy
and oncology treatment if
necessary. Radiotherapy is
providing different modalities
in the treatment for many
children with central nervous
system tumors and recent
improvements in technology
and treatment planning of
radiotherapy offer significant
opportunities for major
therapeutic benefits of a high
probability of long-term
survival with a significant risk
reduction in the development of
complications in the short and
long term in pediatric patients.
REFERENCES
Adan L, Trivin C, Sainte-Rose C, et al. GH deficiency caused by cranial irradiation during childhood: factors and markers in young adults. J Clin Endocrinol Metab 2001;86:5245– 5251.
Baldwin RT, Preston-Martin S. Epidemiology of brain tumors in childhood—a review. Toxicol Appl Pharmacol 2004;199:118–131.
Central Brain Tumor Registry of the United States. CBTRUS.2004. www.cbtrus.org
Donahue B. Short- and long-term complications of radiation therapy for pediatric brain tumors. Pediatr Neurosurg 1992;18:207–217.
Edward C, Halperin. Carlos A, Perez. Luther W, Brady. Principles and Practice of Radiation Oncology. 5ta edición. Editorial Lippincott William & Wilkins. 2008; 1: 1822- 1851.
Gurney JG, Kadan-Lottick NS, Packer RJ, et al. Endocrine and cardiovascular late effects among adult survivors of childhood brain tumors: Childhood Cancer Survivor study. Cancer 2003;97:663–673.
Habrand JL, Abdulkarim B, Beaudré A, et al. La détermination des volumes-cibles en radiothérapie pédiatrique: application aux tumeurs cérébrales. Cancer Radiother 2001, 5: 711-719.
Hopewell JW. Radiation injury to the central nervous system. Med Pediatr Oncol 1998; Suppl 1: 1-9. Review.
Jakacki RI, Goldwein JW, Larsen RL, et al. Cardiac dysfunction following spinal irradiation during childhood. J Clin Oncol 1993;11:1033–1038.
Kirsch DG, Tarbell NJ. New Technologies in Radiation Therapy for Pediatric Brain Tumors: The Rationale for Proton Radiation Therapy. Pediatr Blood Cancer 2004; 42(5): 461-464. Review.
Kooy HM, Dunbar SF, Tarbell NJ, et al. Adaptation of the relocatable Gill-Thomas-Cosman frame in stereotactic radiotherapy. Int J Radiat Oncol Biol Phys 1994; 30(3): 685-691.
Kortmann RD, Timmermann B, Taylor RE, Scarzello G, Plasswilm L, et al. Current and future strategies in radiotherapy of childhood lowgrade glioma of the brain. Part II: treatment-related late toxicity. Strahlenther Onkol 2003; 179(9): 585-597.
Krishnamoorthy P, Freeman C, Bernstein ML, et al. Osteopenia in children who have undergone posterior fossa or craniospinal irradiation for brain tumors. Arch Pediatr Adolesc Med 2004;158:491– 496.
Mazeron JJ, Maugis A, Barret C, Mornex F. Techniques d’irradiation des cancers: la radiothérapie conformationnelle. Paris: Editions Maloine, 2005.
Merchant TE, Fouladi M. Ependymoma: new therapeutic approaches including radiation and chemotherapy. J Neurooncol 2005;75:287–299.
Merchant TE, Hua C, Shukla H, et al. Proton versus photon radiotherapy for common pediatric brain tumors: comparison of models of dose characteristics and their relationship to cognitive function. Pediatr Blood Cancer 2008; 51: 110-117.
Merchant TE, Williams T, Smith JM, et al. Preirradiation endocrinopathies in pediatric brain tumor patients determined by dynamic tests of endocrine function. Int J Radiat Oncol Biol Phys 2002;54:45–50.
Merchant TE, Zhu Y, Thompson SJ, et al. Preliminary results from a Phase II trial of conformal radiation therapy for pediatric patients with localized low-grade astrocytoma and ependymoma. Int J Radiat Oncol Biol Phys 2002; 52(2): 325-332.
Mulhern RK, Palmer SL, Reddick WE, et al. Risks of young age for selected neurocognitive deficits in medulloblastoma are associated with white matter loss. J Clin Oncol 2001;19:472–479.
Narod SA, Stiller C, Lenoir GM. An estimate of the heritable fraction of childhood cancer. Br J Cancer 1991;63:993–999.
Palmer SL, Goloubeva O, Reddick WE, et al. Patterns of intellectual development among survivors of pediatric medulloblastoma: a longitudinal analysis. J Clin Oncol 2001;19:2302–2308.
Reimers TS, Ehrenfels S, Mortensen EL, et al. Cognitive deficits in longRODRÍGUEZ, OROZCO, CHENG: RADIOTERAPIA EN LOS TUMORES CEREBRALES PEDIÁTRICOS 171 term survivors of chilhood brain tumors: Identification of predictive factors. Med Pediatr Oncol 2003; 40: 26-34.
Ricardi U, Corrias A, Einaudi S, Genitori L, Sandri A, et al. Thyroid dysfunction as a late effect in childhood medulloblastoma: a comparison of hyperfractionated versus conventionally fractionated craniospinal radiotherapy. Int J Radiat Oncol Biol Phys 2001; 50(5): 1287-1294.
Rickert CH, Paulus W. Epidemiology of central nervous system tumors in childhood and adolescence based on the new WHO classification. Childs Nerv Syst 2001;17:503–511.
Robertson PL, Muraszko KM, Holmes EJ, et al. Incidence and severity of postoperative cerebellar mutism syndrome in children with medulloblastoma: A prospective study by the Children’s Oncology Group. J Neurosurg 2006; 105: 444- 451.
Schmiegelow M, Lassen S, Weber L,. Dosimetry and growth hormone deficiency following cranial irradiation of childhood brain tumors. Med Pediatr Oncol 1999;33:564–571.
Schoch B, Koncsak J, Dimitrova A, et al. Impact of surgery and adjuvant therapy on balance function in children and adolescents with cerebellar tumors. Neuropediatrics 2006; 37: 350-358.
Sklar CA, Constine LS. Chronic neuroendocrinological sequelae of radiation therapy. Int J Radiat Oncol Biol Phys 1995;31:1113–1121.
Smitt MC, McPeak EM, Donaldson SS. The advantages of threedimensional conformal radiotherapy for treatment of childhood cancer. Radiat Res 1998; 150(5 suppl): S170-S177.
Sonderkaer S, Schmiegelow M, Carstensen H, et al. Long-term neurological outcome of chilhood brain tumors treated by surgery only. J Clin Oncol 2003; 21: 1347-1351.
Surveillance Epidemiology and End Results. SEER 2006. http://seer. cancer.gov/publications
Taylor RE. Current developments in radiotherapy for paediatric brain tumours. Eur J Paed Neurol 2006; 10(4): 167-175. Review.
Wrensch M, Minn Y, Chew T, et al. Epidemiology of primary brain tumors: current concepts and review of the literature. Neurooncology 2002;4:278–299.