2014, Number 1
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Revista Cubana de Cirugía 2014; 53 (1)
Behavior and Rockall risk scoring in the non-variceal upper gastrointestinal bleeding
Ramírez JK, Menéndez RBM, Cobiellas RR
Language: Spanish
References: 39
Page: 17-29
PDF size: 0. Kb.
ABSTRACT
Introduction: non-variceal upper gastrointestinal bleeding is a current surgical emergency of difficult management. This fact prompted the authors to find out its
behavior and to use Rockall risk scoring system to determine the risk of suffering adverse effects during the recovery period, those patients that may be early discharged and the causes that prevent it.
Methods: cross-sectional descriptive study conducted in 182 patients from "Ernesto Guevara de la Serna" general teaching hospital, who were seen in the period of 2009 through 2010.
Results: males were the most affected (54.4 %) and the 60-80 years age group registered the highest number of cases. Gastroduodenal ulcer was the first cause (52.7 %). The initial manifestation was tarry stools in 64 % of cases. Blood hypertension was the most frequent comorbidity (60.7%). In the study group, 44.5% of patients needed blood transfusion. The mortality rate was 8.2 %. Most of patients were classified as intermediate risk cases according to Rockall system (40.1 %). Just 11.5 % of patients were early discharged since the hemodynamic instability (38 %) was the main responsible for this low number. Rockall risk scoring system showed 98.3% sensitivity, 56.9% specificity, 52.3 % positive predictive value, 98.6% negative predictive value and 70.9 % accuracy. The only complication in low risk patients were relapse (1.4 %).
Conclusions: early discharge from hospital occurs in low Rockall risk score patients provided that special attention is paid to hemodynamic stability.
REFERENCES
Feu F, Brulletb E, Calveta X, Fernández-Llamazaresc J, Guardiolaa J, Moreno P. Recomendaciones para el diagnóstico y el tratamiento de la hemorragia digestiva alta aguda no varicosa. Gastroenterol Hepatol. 2003;26(2):70-85.
GurungRB, Joshi G, Gautam N, Pant P, Pokhrel B, Koju R, Bedi TR. Upper gastrointestinal bleeding: etiology and demographic profile based on endoscopic examination at Dhulikhel Hospital, Kathmandu University Hospital. Kathmandu Univ Med J (KUMJ). 2010 Apr-Jun;8(30):208-11.
Emmanuel C. Gorospe, et al. Acute upper gastrointestinal bleeding. Dynamic Medical. [Consultado Marzo 2, 2011] Disponible en: http://dynaweb.ebscohost.com/Detail?sid=41e79dc9-8ª9a -4b5f-97ae- 194eea84ba2b@sessionmgr13&vid=&db=dme&ss=AN+%22114036%22&sl=ll
Pardo Gómez G. Sangramiento digestivo. En: Temas de cirugía. Tomo II. La Habana: Ecimed; 2010. p. 914-22.
Ulloa Capestany JL, Hernández Lara A, Hernández Cardoso AM, García Valdez F, Geroy Gómez CJ. Guía de Práctica Clínica para la hemorragia digestiva alta. Medisur 2009;7(1 Supl):106-11.
Garrido A, Márquez JL, Guerrero FJ, Leo E, Pizarro MA, Trigo C. Cambios en la etiología, resultados y características de los pacientes con hemorragia digestiva aguda grave a lo largo del período 1999-2005. Rev Esp Enferm Dig (Madrid). 2007;99(5):275-279.
Gralnek IM, Barkun AN, Bardou M. Management of Acute Bleeding from a Peptic Ulcer. N Engl J Med. 2008;359(9):928-37.
Vreeburg EM, Terwee CB, Snel P, Rauws EA, Bartelsman JF, Meulen JH, Tytgat GN. Validation of the Rockall risk scoring system in upper gastrointestinal bleeding. U.S. National Library of Medicine. National Institutes of Health. Gut. 1999;44(3):331-5.
Dallal H, Palmer KR, et al. ABC of the upper gastrointestinal tract. Upper gastrointestinal haemorrhage. BMJ, 2001;323:1115. doi: 10.1136; 323.7321.1115.
Wara P, Stødkilde H., et al. Bleeding pattern before admission as guideline for emergency endoscopy.Scand J Gastroenterol. 1985;20(1):72-8.
Manning-Dimmitt LL, DimmittSG, Wilson GR, Diagnosis of Gastrointestinal Bleeding in Adults. American Family Physician. 2005;71(7).
Lewis JD, Bilker WB, Brensinger C, Farrar JT, Strom BL. Hospitalization and mortality rates from peptic ulcer disease and GI bleeding in the 1990s: relationship to sales of nonsteroidal anti-inflammatory drugs and acid suppression medications. Am J Gastroenterol. 2002;97(10):2540-9.
Marmo R, Koch M, Cipolletta L, Capurso L, Grossi E, Cestari R, et al. Predicting mortality in non-variceal upper gastrointestinal bleeders: validation of the Italian PNED Score and Prospective Comparison with the Rockall Score. Am J Gastroenterol. 2010;105(6):1284-91.
Delaney JA, Opatrny L, Brophy JM, Suissa S. Drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding. CMAJ. 2007;177(4):347-51.
Hernández-Díaz S, Rodríguez LA. Steroids and risk of xgastrointestinal complications. Am J Epidemiol. 2001;153(11):1089-93.
Pahor M, Guralnik JM, Ferrucci L, Corti MC, Salive ME, Cerhan JR, et al. Calcium-channel blockade and incidence of cancer in aged populations. Lancet 1996;348(9026):493-7.
Verhamme K, Mosis G, Dieleman J, Stricker B, Sturkenboom M.Spironolactone and risk of upper gastrointestinal events: populationbased case-control study. BMJ 2006;333: doi: 10.1136.
Yuan Y, Tsoi K, Hunt RH. et al. Selective serotonin reuptake inhibitors and risk of upper GI bleeding: confusion or confounding? Am J Med 2006;119(9):719-27.
de Abajo FJ, García-Rodríguez LA. et al. Risk of upper gastrointestinal tract bleeding associated with selective serotonin reuptake inhibitors and venlafaxine therapy: interaction with nonsteroidal anti-inflammatory drugs and effect of acidsuppressing agents. Arch Gen Psychiatry. 2008;65(7):795-803.
Targownik LE, Bolton JM, Metge CJ, Leung S, Sareen J. Selective serotonin reuptake inhibitors are associated with a modest increase in the risk of upper gastrointestinal bleeding. Am J Gastroenterol. 2009;104(6):1475-82.
Scottish Intercollegiate Guidelines Network. Management of acute upper and lower gastrointestinal bleeding. Edinburgh: Elliott House, Hillside Crescent; 2008.
Barkun AN, Bardou M, Kuipers EJ, Sung J, Hunt RH, Martel M, Sinclair P, International Consensus Upper Gastrointestinal Bleeding Conference Group. Management of Nonvariceal Upper Gastrointestinal Bleeding. Annals of Internal Medicine. 2010;152:101-13.
Rockall TA, Logan RF, Devlin HB, Northfield TC. Risk assessment after acute upper gastrointestinal hemorrhage. U.S. National Library of Medicine National Institutes of Health. Gut. 1996;38(3):316-21.
Palmer K, Nairn M. et al. Management of acute gastrointestinal blood loss: summary of SIGN guidelines. BMJ 2008;337:a1832 doi: 10.1136; a1832.
Imperiale TF, Dominitz JA, Provenzale DT, Boes LP, Rose CM, BowersJC, et al. Predicting poor outcome from acute upper gastrointestinal hemorrhage. Arch Intern Med. 2007;167(12):1291-6.
Thomsen RW, Riis A, Christensen S, Nørgaard M, Sørensen HT. Diabetes and 30-Day Mortality from Peptic Ulcer Bleeding and Perforation. Diabetes Care. 2006;29(4):805.
Lung E, et al. Evaluation and Management of Gastrointestinal Bleeding. Part 1: Nonvariceal Upper Gastrointestinal Bleeding. Gastroenterology 2004;4(4):186-91.
American College of Radiology (ACR). Appropriateness Criteria for upper gastrointestinal bleeding. National Guideline Clearinghouse 2011;23:821.
McDonald H, Burroughs AK, Feagan BG., Fennerty MB. Evidence Based Gastroenterology & Hepatology. Garsington Road: Editorial John Wiley and Sons Ltd; 2010.
Church NI, Dallal HJ, John Masson, Mowat AG, Johnston DA, Radin E, et al. Validity of the Rockall scoring system after endoscopic therapy for bleeding peptic ulcer: a prospective cohort study. Gastrointestinal Endoscopy 2006;63(4):606-12.
Raiden AK,Bonadero RG, et al.Valor predictivo del Score de Rockall en hemorragia digestiva alta. Gastroenlared. [revisado Julio 16,2011] Disponible en: http://www.gastroenlared.com/template.php?pagina=./Articulos/VI_5/HDA.htm
Jurado Hernández AM, de Teresa Galván J, Ruiz-Cabello Jiménez M, Pinel Julián LM. Evolución en la epidemiología de la hemorragia digestiva alta no varicosa desde el año 1985 hasta 2006. Rev. Esp. Enferm. Dig 2008;100(5).
Stanley AJ, Ashley D, Dalton HR, MowatC, Gaya DR, Thompson E, et al. Outpatient management of patients with low-risk upper-gastrointestinal haemorrhage: multicentre validation and prospective evaluation. The Lancet 2009;373(9657):42-7.
Patel MD. Retrospective evaluation of the Rockall risk scoring system in patients with nonvariceal upper gastrointestinal hemorrhage at a community hospital. [Thesis]. Ypsilanti, Michigan: Eastern Michigan University. October 20, 2006.
Soncini M, Omerob T, Pietroc L, et al. Management of patients with nonvariceal upper gastrointestinal hemorrhage before and after the adoption of the Rockall score, in the Italian Gastroenterology Units. Eur J Gastroenterology & Hepatology. 2007;19(7):543-7.
Chan J, Lakshmana Ayaru et al. Analysis of risk scoring for the outpatient management of acute upper gastrointestinal bleeding. Frontline Gastroenterol 2010; doi:10.1136/fg.2010.002436
Espinoza Ríos J, Huerta Mercado Tenorio J, Lindo Ricce M, García Encinas C, Ríos Matteucci S, Vila Gutiérrez S, et al. Validación del Score de Rockall en Pacientes con Hemorragia Digestiva Alta en un Hospital de Lima-Perú. Rev. Gastroenterol. Perú. 2009;29(2):111-7.
Cruz Alonso JR, Anaya González JL, Pampín Camejo LE, Pérez Blanco D, Lopategui Cabezas I. Mortalidad por sangrado digestivo alto en el Hospital "Enrique Cabrera". Rev Cubana Cir. 2008; 47(4). [citado 8 de mayo de 2013] Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034 - 74932008000400006&lng=es
Almeida Varela R, Pérez Suárez F, Díaz Elías JO, Martínez Hernández JA. Comportamiento de la hemorragia digestiva alta en el Hospital Universitario "Calixto García". Rev Cubana Cir. 2011;5040-53. [citado 8 de mayo de 2013] Disponible en: http://www.redalyc.org/articulo.oa?id=281223026004