2014, Number 1
Tratamiento conservador en pacientes con enfermedad arterial periférica en estadio Rutherford 1-5
Language: Spanish
References: 16
Page: 4-7
PDF size: 186.97 Kb.
ABSTRACT
Aim. To demonstrate what the use of cilostazol in symptomatic patients with peripheral arterial disease (PAD) may improve short-term clinical stage.Material and methods. We performed a cohort study during the period October 2011 to July 2013, in the office located in Metepec, Estado de México, identifying patients with (PAD) who had intermittent claudicaction, critical limb ischemic (CLI) and punctate ischemic ulcers, who had been revascularized of the limb contralateral limb symptoms in non revascularized with high surgical risk to under go open surgery or endovascular procedure and those who had no financial resources for such intervention.
Results. In 67 patients, 38 men (56.7%) and 29 women (43.3%), with a mean age of 72.6 years, with a history of importance: 37.3% smoking, 73.1% diabetes and 56.7% hypertension. Reduction was found Rutherford in 87% of patients, in the subgroup of patients with diabetes there was a reduction of Rutherford 5 to Rutherford 1 and patients without diabetes of Rutherford 4 to Rutherford 2. The presentation of adverse effects with the use of cilostazol was 19% of patients.
Conclussion. The results of this study showed that cilostazol may reduced the severity of PAD in patients not candidates for revascularization with few adverse effects, even in patients with stage Rutherford 4 and 5.
REFERENCES
Hirsch AT, Haskal ZJ, Hertzer NR, et al. ACC/AHA 2005 guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric and abdominal aortic): executive summary a collaborative report from the American Association for Vascular Surgery, Society for Vascular Surgery, Society for Cardiovascular Angiography and Intervention, Society for Vascular Medicine and Biology, Society for Interventional Radiology and the ACC/AHA Task Force on Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients with Peripheral Arterial Disease) endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation; National Heart, Lung and Blood Institute; Society for Vascular Nursing; TransAtlantic Inter-Society Consensus; and Vascular Disease Foundation. J Am Coll Cardiol 2006; 47: 1239-312.
Regensteiner J, Ware JJ, McCarthy W, et al. Effect of cilostazol on treadmill walking, community-based walking ability, and health-related quality of life in patients with intermittent claudication due to peripheral arterial disease: meta-analysis of six randomized controlled trials. J Am Geriatr Soc 2002; 50: 1939-46.