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2014, Number 3

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Revista Habanera de Ciencias Médicas 2014; 13 (3)

Frequency of isolation of methicillin resistant Staphylococcus aureus in

Mederos HJ, Morejón GM

Language: Spanish
References: 23
Page: 406-416
PDF size: 130.27 Kb.


ABSTRACT

Introduction: Staphylococcus aureus is one of the most important pathogens in the clinical setting, both for the broad spectrum of infections it causes and the increasing antibiotic resistance. Special attention is regarded to methicillin-resistant clones (MRSA), which provide not only resistance to all beta-lactamic agents, but carry multiple resistance genes.
Objective: to characterize epidemiologically MRSA isolations in patients hospitalized in "Comandante Manuel Fajardo" hospital in the time period between the 1st of June and December 31st, 2012.
Material and Methods: a retrospective study was performed between the 1st of June and December 31st, 2012, which included patients admitted in the hospital during that time in which at least 1 isolation of MRSA was made. Methillicin resistance was determined by using 30 µg cefoxitin discs.
Results: although it was not possible to use cefoxitin discs as resistance marker in about a quarter of total S. aureus isolations, a high incidence of MRSA was found (64,2%). The vast majority of isolations came from skin and soft tissues infection. Angiology and Dermatology services had 60,0% of isolations. The greatest antimicrobial sensitivity was for vancomycin, amikacin, chloramphenicol, tetracycline and ciprofloxacin.
Conclusions: MRSA clones are both an international problem and a reality in our hospital; they must be properly identified in order to start the right treatment.


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