Reyes VJM, Lara MM, Díaz OSE, Morales MI, González GEL

Language: Spanish
References: 20
Page: 31-37
PDF size: 235.99 Kb.

ABSTRACT

In order to characterize the gastrointestinal manifestations in patients with American trypanosomiasis a descriptive cross-sectional study was conducted in a population consisting of 130 patients with positive IgG antibodies to Trypanosoma cruzi treated at the “Victoria South” Medical Center of integral diagnostic from José F. Ribas, municipality, Aragua State, Bolivarian Republic of Venezuela, from March 2012 to February 2013. The most affected age group was 61 years and over and not predominantly found in sex; asymptomatic patients predominated, followed by those with digestive symptoms; gingivostomatitis was the clinical finding was found, followed dyspeptic disorders and hepatomegaly, megacolon with chronic constipation, esophageal achalasia and megaesophagus. Hepatitis B was detected in four patients and C in two.

REFERENCES

1. Llovet I, Dinardi G, De Maio FG. Mitigating social and health inequities: community participation and Chagas disease in rural Argentina. Glob Public Health. 2011 Jun;6(4):371-84.

2. Bowman NM, Kawai V, Gilman RH, Bocangel C, Galdos-Cardenas G, Cabrera L, et al. Autonomic dysfunction and risk factors associated with Trypanosoma cruzi infection among children in Arequipa, Peru. Am J Trop Med Hyg. 2011 Jan;84(1):85-90.

3. Guerrero L, Pinazo MJ, Posada E, Gascón J, Ribas J, Soy DK. A high-performance liquid chromatographic method for benznidazole quantitation in plasma of patients with Chagas disease. Clin Chem Lab Med. 2011 Jan;49(1):77-82. doi: 10.1515/CCLM.2011.014 Epub 2010 Nov 18.

4. Carod-Artal FJ. American tripanosomiasis. Handb Clin Neurol. 2013;114:103-23. doi: 10.1016/B978-0-444-53490-3.00007-8

5. Gilber SR, Alban SM, Gobor L, Bescrovaine Jde O, Myiazaki MI, Thomaz-Soccol V. Comparison of conventional serology and PCR methods for the routine diagnosis of Trypanosoma cruzi infection. Rev Soc Bras Med Trop. 2013 May-Jun;46(3):310-5. doi: 10.1590/0037-8682-0046-2013.

6. Cervantes-Landín AY, Martínez-Martínez I, Reyes PA, Shabib M, Espinoza-Gutiérrez B. Standardization of Dot-ELISA for detection of anti-Trypanosoma cruzi antibodies, compared to ELISA and Western blot. Enferm Infecc Microbiol Clin. 2013 Jul 24 pii: S0213-005X(13)00169-9. doi: 10.1016/j.eimc.2013.05.006.

7. Dos Santos JP, Lima-Costa MF, Peixoto SV. Nutritional aspects associated with chronic Trypanosoma cruzi (Chagas 1909) infection among older adults: Bambuí Project. Cad Saude Publica. 2013 Jun;29(6):1141-8.

8. Cesa K, Caillouët KA, Dorn PL, Wesson DM. High Trypanosoma cruzi (Kinetoplastida: Trypanosomatidae) prevalence in Triatoma sanguisuga (Hemiptera: Redviidae) in southeastern Louisiana. J Med Entomol. 2011 Sep;48(5):1091-4.

9. Schechter RB, Lemme EM, Novais P, Biccas B. Achalasia in the elderly patient: a comparative study. Arq Gastroenterol. 2011 Jan-Mar;48(1):19-23.

10. Santana Kde S, Bavia ME, Lima AD, Guimarães IC, Soares ES, Silva MM, et al. Spatial distribution of triatomines (Reduviidae: Triatominae) in urban areas of the city of Salvador, Bahia, Brazil. Geospat Health. 2011 May;5(2):199-203.

11. Grijalva MJ, Villacís AG, Ocaña-Mayorga S, Yumiseva CA, Baus EG. Limitations of selective deltamethrin application for triatomine control in central coastal Ecuador. Parasit Vectors. 2011 Feb 18;4:20. doi: 10.1186/1756-3305-4-20.

12. Pineda V, Saldaña A, Monfante I, Santamaría A, Gottdenker NL, Yabsley MJ, et al. Prevalence of trypanosome infections in dogs from Chagas disease endemic regions in Panama, Central America. Vet Parasitol. 2011 Jun 10;178(3-4):360-3. doi: 10.1016/j.vetpar.2010.12.043. Epub 2011 Jan 11

13. Fabbro DL, Olivera V, Bizai ML, Denner S, Diez C, Mancipar I, et al. Humoral immune response against P2β from Trypanosoma cruzi in persons with chronic Chagas disease: its relationship with treatment against parasites and myocardial damage. Am J Trop Med Hyg. 2011 Apr;84(4):575-80.doi: 10.4269/ajtmh.2011.10-0261.

14. Añez N, Crisante G, Caraballo F, Delgado W, Parada H. Trypanosoma cruzi persistence at oral inflammatory foci in chronic chagasic patients. Acta Trop. 2011 Mar;117(3):207-11. doi: 10.1016/j.actatropica.2010.12.010. Epub 2011 Jan 5.

15. Jackson Y, Alirol E, Getaz L, Wolff H, Combescure C, Chappuis F. Tolerance and safety of nifurtimox in patients with chronic chagas disease. Clin Infect Dis. 2010 Nov 15;51(10):e69-75. doi: 10.1086/656917 Epub 2010 Oct 8.

16. Carrera-Silva EA, Guiñazu N, Pellegrini A, Cano RC, Arocena A, Aoki MP, et al. Importance of TLR2 on hepatic immune and non-immune cells to attenuate the strong inflammatory liver response during Trypanosoma cruzi acute infection. PLoS Negl Trop Dis. 2010 Nov 2;4(11):e863. doi: 10.1371/journal.pntd.0000863

17. Neto JP, Lyra IM, Reis MG, Goncalves MS. The association of infection and clinical severity in sickle cell anaemia patients. Trans R Soc Trop Med Hyg. 2011 Mar;105(3):121-6. doi: 10.1016/j.trstmh.2010.11.007..Epub 2011 Jan 8

18. Da Silveira AB, de Oliveira EC, Neto SG, Luquetti AO, Fujiwara RT, Oliveira RC, et al. Enteroglial cells act as antigen-presenting cells in chagasic megacolon. Hum Pathol. 2011 Apr;42(4):522-32.doi: 10.1016/j.humpath.2010.06.016 Epub 2011 Jan 3.

19. Vicentine FP, Herbella FA, Allaix ME, Silva LC, Patti MG. Comparison of idiopathic achalasia and Chagas' disease esophagopathy at the light of high-resolution manometry. Dis Esophagus. 2014 Feb-Mar;27(2):128-33. doi: 10.1111/dote.12098. Epub 2013 Jun 24.

20. De Souza DH, Vaz Mda G, Fonseca CR, Luquetti A, Rezende Filho J, de Oliveira EC. Current epidemiological profile of Chagasic megaesophagus in Central Brazil. Rev Soc Bras Med Trop. 2013 May-Jun;46(3):316-21. doi: 10.1590/0037-8682-0065-2013.