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2011, Number 1

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RCAN 2011; 21 (1)

Inmunonutrición y trauma

Nicolás MAL, Ferraresi ZE

Language: Spanish
References: 27
Page: 129-146
PDF size: 316.17 Kb.


ABSTRACT

Immunonutrition has become a subspecialty of nutritional support arising many expectations since the arrival to the market of enteral products lines which incorporated nutrients with a pharmacological action specifically oriented to modulate the activity of the immune system. Notwithstanding the promises implied in the use of such “immunomodulation diets”, the truth is results documented up to this date from clinical trials have failed in reveal real benefits. There are even contradictory reports stating that administration of such diets could be harmful for patients assisted with trauma. The present review pretends to review the subject, to assess the results observed after the use of the “immunomodulation diets” in the trauma patient, and to put in perspective these discordant reports, as well as to set forth recommendations for their administration, along with the design of infusion schemes and actions for monitoring such therapies.


REFERENCES

  1. Bihari D. Immunonutrition in the critically ill. JPEN J Parenter Enteral Nutr 2002; 26:67-9.

  2. Kecskes C. Soporte nutricional en el paciente traumatizado. En: Terapia Intensiva SATI (Editor: Ceraso D). Cuarta Edición. Editorial Panamericana. Buenos Aires: 2007. pp 1039-1044.

  3. Arenas Márquez H, Arenas Moya D. Inmunonutrición. En: Nutrición enteral y parenteral (Editores: Arenas Márquez H, Anaya Prado R). Primera Edición. MacGraw-Hill Interamericana. Ciudad México: 2007. pp 174-184.

  4. Stahel PF, Smith WR, Moore EE. Role of biological modifiers regulating the immune response after trauma. Injury 2007;38:1409-22.

  5. Khorana J, Rerkasem K, Apichartpiyakul C et al. Immunonutrition and cytokine response in patients with head injury. J Med Assoc Thai 2009;92:188-94.

  6. Berger MM, Binnert C, Chiolero RL, Taylor W, Raffoul W, Cayeux MC, Benathan M, Shenkin A, Tappy L. Trace element supplementation after major burns increases burned skin trace element concentrations and modulates local protein metabolism but not wholebody substrate metabolism. Am J Clin Nutr 2007;85:1301-6.

  7. Chuntrasakul C, Siltham S, Sarasombath S, Sittapairochana C et al. Comparison of a immunonutrition formula enriched arginine, glutamine and omega-3 fatty acid, with a currently high-enriched enteral nutrition for trauma patients. J Med Assoc Thai 2003;86:552-61.

  8. Tashiro T. N-3 polyunsaturated fatty acids in pharmaconutrition and inmunonutrition. J Gastroenterol 2000; 35(Suppl 12):24.

  9. Hasselmann M, Reimund JM. Lipids in the nutritional support of the critically ill patients. Curr Opin Crit Care 2004; 10:449-55.

  10. Mayer K, Seeger W. Fish oil in critical illness. Curr Opin Nutr Metab Care 2008;11: 121-7.

  11. Spindler-Vesel A, Bengmark S, Vovk I, Cerovic O, Kompan L. Synbiotics, prebiotics, glutamine or peptide, in early enteral nutrition: a randomized study in trauma patients. JPEN J Parenter Enteral Nutr 2007;31:119-26.

  12. Soguel L, Chioléro RL, Ruffieux C, Berger MM. Monitoring the clinical introduction of a glutamine and antioxidant solution in critically ill trauma and burn patients. Nutrition 2008;24:1123-32.

  13. Canadian Practice Group. Critical Care Clinical Practice Guidelines. Kingston, Ontario, Canada: 2009. Disponible en: http://www.criticalcarenutrition.com/doc s/cpg/4.1a_arginine_FINAL.pdf. Consultado por última vez: 28 de Diciembre del 2010.

  14. Suchner U, Kuhn KS, Fürst P et al. The scientific basis of immunonutrition. Proc Nutr Soc 2000;59:553-63.

  15. Schneider H, Atkinson SW. Immunonutrition- fact or fad. J Nutr Health Aging 2000; 4:120-3.

  16. Bastian L, Weimann A. Immunonutrition in patients after multiple trauma. Br J Nutr 2002; 87(Suppl 1):S133-S134.

  17. McCowen KC, Bistrian BR. Immunonutrition: problematic or problem solving? Am J Clin Nutr 2003; 77:764-70.

  18. Saito H. Immunonutrition. Nippon Geka Gakkai Zasshi 2004;105:213-7.

  19. Grimble RF. Immunonutrition. Curr Opin Gastroenterol 2005;21:216-22.

  20. Jeejeebhoy KN. Enteral feeding. Curr Opin Gastroenterol 2005;21:187-91.

  21. Marik PE, Zaloga GP. Immunonutrition in critically ill patients: a systematic review and analysis of the literature. Intensive Care Med 2008;34:1980-90.

  22. De Jonghe B, Appere-De-Vechi C, Fournier M, Tran B, Merrer J, Melchior JC, Outin H. A prospective survey of nutritional support practices in intensive care unit patients: What is prescribed? What is delivery? Crit Care Med 2008;24:215-22.

  23. Martinuzzi A, Ferraresi E, Orsatti M et al. Estado del soporte nutricional en una unidad de Cuidados críticos. RNC Publicación científica sobre Nutrición clínica 2011;20:5-12.

  24. Jonesa N, Heyland DK. Pharmaconutrition: a new emerging paradigm. Curr Opin Gastroenterol 2008;24:215- 22.

  25. Buchmam AL. Glutamine: commercially essential or conditionally essential? A critical appraisal of the human data. Am J Clin Nutr 2001;74:25-32.

  26. Schulman AS, Willcutts KF, Claridge JA et al. Does the addition of glutamine to enteral feeds affect patient mortality? Crit Care Med 2005;33:2501-6.

  27. Zhou M, Martindale R. Immunemodulating enteral formulations: optimum components, appropriate patients, and controversial use of arginine in sepsis. Current Gastroenterology Reports 2007; 9:329-37.




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