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2011, Number 1

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CorSalud 2011; 3 (1)

Postoperative analgesic efficacy of epidural morphine in myocardial bypass surgery

Hernández OR, González AO, Hidalgo MPA, Marrero FIM, Rodríguez JM, Méndez MJ, García CS, González MM

Language: Spanish
References: 56
Page: 15-25
PDF size: 272.30 Kb.


ABSTRACT

Introduction and objectives: Epidural analgesia is a cornerstone in cardiac surgery. The aim of this study was to compare the use of lyophilized morphine and epidural bupivacaine analgesia in postoperative surgery for the surgery of the coronary arteries. Method: A prospective and inferential study was performed in 20 patients divided into two groups. The group M received epidural analgesia with 2 mg of morphine associated to 100 mg of bupivacaine and group B only bupivacaine. Results: Males were predominant. The average ages and weights of both groups were similar (p›0,05). 90 % of the patients in group M had excellent analgesia at 8 hours after surgery and remained from good to excellent at 12 and 24 hours. While 50 % of patients in group B referred regular analgesia at 8 hours after the operation, which extended to 80% of patients at 12 hours. In the 24-hour monitoring, all patients in group B complained of poor or inadequate analgesia (p‹0,05). The average total time of postoperative analgesia obtained in group M was 28.37 hours and group B, of 8.86 hours (p‹0,01). The main adverse effects were hypotension and bradycardia. Conclusions: Morphine proved useful as an analgesic in surgery of the coronary arteries. Patients with bupivacaine and epidural morphine had better analgesia and for a longer time than patients treated with bupivacaine alone.


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