medigraphic.com
ISSN 0188-9796 (Print)

2013, Number 4

<< Back Next >>

Rev Endocrinol Nutr 2013; 21 (4)

Relationship of neck circumference to glucose and acanthosis nigricans

Hernández-Escalante VM, Cabrera-Araujo Z, Euán-Braga G

Language: Spanish
References: 22
Page: 159-163
PDF size: 189.92 Kb.


ABSTRACT

Background: Neck circumference (NC) emerges as a risk indicator for insulin resistance and is easy to measure; however there is no consensus with cutoffs. Methods: We included adults of 18-59 years. Percentiles were established 75, 85 and 95 for NC. We determined association with acanthosis nigricans and capillary blood glucose. Results: NC was measured on 507 subjects with a mean age of 37.08 years. Mean NC was 37.65 cm and 33.9 cm in men and women. The percentile 85 stood at 40.0 cm in men and 34.0 cm in women in the group aged 18-24 years and 42 and 38 cm respectively in the group of 25-59 years. An elevated NC (≥ 35 cm in women and ≥ 39 cm in men) was strongly associated with acanthosis nigricans in both age groups: OR 13.3 (3.1, 33.2, p ‹ 0.01) in the 18-24 age group and OR 27.4 (8.5, 88.1, p ‹ 0.01) in the group of 25-59 years, being greater than the associations found with BMI ≥ 30 and elevated waist (women: 88 cm, men: 102 cm). The correlation glucose/NC was greater than glucose/BMI (r = 0.388, p ‹ 0.001, and r = 0.197, p ‹ 0.03, respectively) and mean glucose was greater in the elevated NC: 106.36 mg/dL and 94.63, respectively (p ‹ 0.001). Conclusions: The neck circumference was associated with acanthosis nigricans more strongly than BMI or waist. In addition, glucose was correlated on subjects of 25-59 years.


REFERENCES

  1. Ben-Noun L, Sohar E, Laor A: Neck circumference as a simple screening measure for identifying overweight and obese patients. Obes Res. 2001; 9: 470-477.

  2. Ben-Noun L, Laor A: Relationship of neck circumference to cardiovascular risk factors. Obes Res. 2003; 11: 226-231.

  3. Lapunzina P, Aiello H: Manual de antropometría normal y patológica. Barcelona, España: Ed Masson; 2002.

  4. Alfie J, Díaz M, Páez O, Cufaro P, Rodríguez P, Fábregues G et al: Relación entre la circunferencia del cuello y el diagnóstico de hipertensión arterial en el Registro Nacional de Hipertensión Arterial (RENATA). Rev Argent Cardiol. 2012; 80: 275-279.

  5. Sjöström CD, Hakangard AC, Lissner L, Sjöström L: Body compartment and subcutaneous adipose tissue distribution-risk factor patterns in obese subjects. Obes Res. 1995; 3: 9-22.

  6. Laakso M, Matilainen V, Keinänen-Kiukaanniemi S: Association of neck circumference with insulin resistance-related factors. Int J Obes Relat Metab Disord. 2002; 26: 873-875.

  7. Yan Q, Sun D, Li X, Zheng Q, Li L, Gu C, Feng B: Neck circumference is a valuable tool for identifying metabolic syndrome and obesity in Chinese elder subjects: a community-based study. Diabetes Metab Res Rev. 2013 Sep. 2. doi: 10.1002/dmrr.2464.

  8. Preis SR, Massaro JM, Hoffmann U, D’Agostino RB Sr, Levy D, Robins SJ et al: Neck circumference as a novel measure of cardiometabolic risk: the Framingham Heart study. J Clin Endocrinol Metab. 2010; 95: 3701-3710.

  9. Dixon JB, O’Brien PE: Neck circumference a good predictor of raised insulin and free androgen index in obese premenopausal women: changes with weight loss. Clin Endocrinol (Oxf). 2002; 57: 769-778.

  10. Pinheiro AC, Rojas P, Carrasco F, Gómez P, Mayas N, Morales I: Acanthosis nigricans an indicator of insulin resistance in Chilean adult population. Nutr Hosp. 2011; 26: 940-944.

  11. Stoddart ML, Blevins KS, Lee ET, Wang W, Blackett PR: Association of acanthosis nigricans with hyperinsulinemia compared with other selected risk factors for type 2 diabetes in Cherokee Indians: The Cherokee Diabetes Study. Diabetes Care. 2002; 25: 1009-1014.

  12. Sadeghian G, Ziaie H, Amini M, Nilfroushzadeh MA: Evaluation of insulin resistance in obese women with and without acanthosis nigricans. J Dermatol. 2009; 36: 209-212.

  13. Patidar PP, Ramachandra P, Philip R, Saran S, Agarwal P, Gutch M, Gupta KK: Correlation of acanthosis nigricans with insulin resistance, anthropometric, and other metabolic parameters in diabetic Indians. Indian J Endocrinol Metab. 2012; 16: S436-S437.

  14. Ferraz DP, Maia FF, Araujo LR: Fingerstick capillary glycemia versus ear lobe measurement: comparative analysis or results and patient preferences. Arq Bras Endocrinol Metabol. 2004; 48: 389-393.

  15. Soussi D, Khoudri I, Bennis RN, Abidi K, Cherrah Y, Zeggwagh AA, Abouqal R: Evaluation of the reality of capillary glycemia measurement in an intensive care unit. Ann Biol Clin (Paris). 2006; 64: 77-81.

  16. Vázquez JL, Gómez H, Fernández S: Diabetes mellitus in an adult population of the IMSS (Mexican Institute of Social Security). Rev Med Inst Mex Seguro Soc. 2006; 44: 13-26.

  17. Zueger T, Schuler V, Stettler C, Diem P, Christ ER: Assessment of three frequently used blood glucose monitoring devices in clinical routine. Swiss Med Wkly. 2012; 142: w13631. doi: 10.4414/smw.2012.13631.

  18. Nafiu OO, Burke C, Lee J, Voepel-Lewis T, Malviya S, Tremper KK: Neck circumference as a screening measure for identifying children with high body mass index. Pediatrics. 2010; 126: e306-e310. doi:10.1542/peds.2010-0242.

  19. Nafiu OO, Zepeda A, Curcio C, Prasad Y: Association of neck circumference and obesity status with elevated blood pressure in children. J Hum Hypertens. 2013 Oct. 3. doi: 10.1038/jhh.2013.93.

  20. Androutsos O, Grammatikaki E, Moschonis G, Roma-Giannikou E, Chrousos GP, Manios Y, Kanaka-Gantenbein C: Neck circumference: a useful screening tool of cardiovascular risk in children. Pediatr Obes. 2012; 7: 187-195. doi: 10.1111/j.2047-6310.2012.00052.x. Epub 2012 Apr 13.

  21. Guo X, Li Y, Sun G, Yang Y, Zheng L, Zhang X, Sun Z, Ma H, Wang N, Jiang M, Li J, Sun Y: Prehypertension in children and adolescents: association with body weight and neck circumference. Intern Med. 2012; 51: 23-27.




2020     |     www.medigraphic.com