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ISSN 0185-3252 (Print)
Revista de la Asociación Médica del Centro Médico ABC

2014, Number 1

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An Med Asoc Med Hosp ABC 2014; 59 (1)

Treatment of primary hyperparathyroidism by targeted parathyroidectomy with intraoperative parathyroid hormone measurement

Aguirre GMP, Díaz CD, Posada TJA, Acosta BV, Ortiz HC, Peña GJF, Stoopen ME, Alvarado BR, Herrera HMF

Language: Spanish
References: 21
Page: 36-40
PDF size: 224.04 Kb.


ABSTRACT

Background: Surgical treatment of primary hyperparathyroidism (HPT) by targeted parathyroidectomy and intraoperative determination of parathyroid hormone (PTH) has gained acceptance among surgeons. The aim of this study was to assess our results with this approach. Material and methods: This is a descriptive, observational study of 79 patients who underwent targeted parathyroidectomy with intraoperative measurement of PTH at the ABC Medical Center between June, 2007 and December, 2012. Demography, presentation, laboratory findings, image studies, surgical treatment, intraoperative PTH changes and outcomes were analyzed. Results: All patients had biochemical diagnosis of primary primary hyperparathyroidism and at least one image study showing uniglandular disease. PTH levels 10-15 minutes after the excision of the adenoma suggested cure of the disease (reduction › 50% of the preoperative levels or normalization) in 77 patients. From the group of patients with biochemical criteria of cure, one patient presented postoperative hypercalcemia (98.7%). Surgical reexploration established the diagnosis of parathyroid hyperplasia. Histological study confirmed a single adenoma in 77 patients and a double adenoma in two. Conclusions:In our institution, targeted parathyroidectomy with intraoperative measurement of PTH is safe and effective. Our results are similar to those from other centers.


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