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2005, Number 1

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Gac Med Mex 2005; 141 (1)

CD1 pathway and NK T cell activation to glycolipid antigens from Mycobacterium tuberculosis.

Sada-Ovalle I, Torre-Bouscoulet L, Jiménez-Martínez MC, Martínez-Cairo S, Zenteno E, Lascurain R

Language: Spanish
References: 73
Page: 35-42
PDF size: 108.56 Kb.


ABSTRACT

The aim of this review is to analyze the current state of our knowledge about cell surface molecules involved in glycolipid antigen presentation, named CD1 family. These proteins constitute a third class of antigen-presenting molecules. CD1 molecules develop diverse important immune functions in host defenses against microbial infections. In recent years these proteins have been involved in the generation of cell-mediated immune response against Mycobacterium tuberculosis. Here, we analyze relevant roles of CD1 proteins and glycolipid antigen-specific T cells.


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