Sada-Ovalle I, Torre-Bouscoulet L, Jiménez-Martínez MC, Martínez-Cairo S, Zenteno E, Lascurain R

Idioma: Español
Referencias bibliográficas: 73
Paginas: 35-42
Archivo PDF: 108.56 Kb.

RESUMEN

El objetivo de esta revisión es analizar el estado actual de nuestro conocimiento sobre las moléculas de superficie celular involucradas en la presentación de antígenos glicolipídicos, denominadas familia CD1. Estas proteínas constituyen la tercera clase de moléculas presentadoras de antígeno. Las proteínas CD1 controlan diversas funciones inmunes importantes en la defensa del hospedero contra las infecciones microbianas. En años recientes estas proteínas han sido involucradas en la generación de una respuesta inmune celular contra Mycobacterium tuberculosis. Aquí, nosotros analizaremos aspectos relevantes acerca de las proteínas CD1 y las células T específicas para antígenos glicolipídicos.

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