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2014, Number 2

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Rev Odont Mex 2014; 18 (2)

In vitro efficiency of fluoride-containing compounds on remineralization of carious enamel lesions under cyclic pH conditions

Prado RSG, Araiza TMÁ, Valenzuela EE

Language: Spanish
References: 35
Page: 96-104
PDF size: 377.30 Kb.


ABSTRACT

Fluoride-containing products are mainly used due to their anti-cariogenic effect upon dental enamel. Objective: The aim of the present study was to determine the efficiency of three fluorinated compounds when used on demineralized enamel. Method: A de-mineralized surface was obtained by means of exposing the enamel of 120 permanent third molars to a demineralizing solution for 96 hours. Molars were randomly divided into four groups in order to receive topical treatment with the following fluorinated compounds: 1) silver ammonium fluoride, 2) difluorsilane, 3) acidulated phosphate fluoride and 4) a control group. All samples were immersed in a cyclic pH system (pH 4.4 to 7.0) and retrieved after 5, 10 and 15 days in order to be observed. Samples were examined under polarized light and Tholuet solution in a photomicroscope (Zeiss, Germany) in order to determine remineralization according to exhibited birefringence. Results: After 5 and 10 days, the group treated with silver ammonium fluoride showed significant difference with respect to other groups. Nevertheless, acidulated phosphate fluoride 10-day results remained equally unaltered at 15 days. Conclusions: The group treated with silver ammonium fluoride presented more significant changes than groups treated with silver ammonium fluoride, difluorsilane as well as the control group.


REFERENCES

  1. Menaker L. Bases biológicas de la caries dental. España: Ed. Salvat: 1986. pp. 199-209.

  2. LeGeros ZR. Calcium phosphates in oral biology and medicine. Monographs in oral science. Vol. 15. EUA: Ed. Karger; 1991. pp. 108-129.

  3. Lazzari EP. Bioquímica dental. 2a. ed. México: Ed. Interamericana; 1978. pp. 236-247.

  4. ten Cate JM, Duijsters PPE. Alternating demineralization and remineralization of artificial enamel lesions. Caries Res. 1982; 16: 201-210.

  5. Carlos JP. Fluoride mouthrinses, in clinical uses of fluorides. Wei SHY. EUA, Philadelphia: Ed. Lea and Febiger; 1985. pp. 153-173.

  6. Monterde CME, Delgado RJM, Martínez RM, Guzmán FCE, Espejel MM. Desmineralización-remineralización del esmalte dental. ADM. 2002; 59 (6): 220-222.

  7. Lippert F, Parker DM, Jandt KD. In vitro demineralization/remineralization cycles at human tooth enamel surfaces investigated by AFM and nanoindentation. J Coll Interf Sc. 2004; 280: 442-448.

  8. Itthagarun A, Wei SHY, Wefel JS. The effect of different commercial dentifrices on enamel lesion progression: an in vitro pH-cycling study. Int Den J. 2000; 50: 21-28.

  9. Thylstrup A, Fejerskov O. Caries. Barcelona: Ed. Doyma; 1988. pp. 254-272.

  10. Rolla G, Ogaard B, De Almeida CR. Topical application of fluorides on teeth. New concepts of mechanisms of interaction. J Clin Periodontol. 1993; 20: 105-108.

  11. Mathewson RJ, Primosch RE. Fundamentals of pediatric dentistry. 3a. ed. Chicago: Ed. Quintessence Publishing Co; 1995. pp. 105-111.

  12. Ingram GS, Nash PF. A mechanism for the anticaries action of fluoride. Caries Res. 1980; 14: 298-303.

  13. ten Cate JM. Current concepts on the theories of the mechanism of action of fluoride. Acta Odontol Scand. 1999; 57: 325-329.

  14. Seif T et al. Cariología. Prevención, diagnóstico y tratamiento contemporáneo de la caries dental. Venezuela: Ed. AMOLCA; 1997. pp. 243-250.

  15. Escobar F. Odontología pediátrica. Colombia: Ed. AMOLCA; 2004. pp. 132-134.

  16. Hazelrigg CH, Dean J, Fontana M. Fluoride varnish concentration gradient and its effect on enamel demineralization. Pediatr Dent. 2003; 25 (2): 119-126.

  17. Björg A. Fluoride uptake by enamel surfaces, root surfaces and cavity walls following application of a fluoride varnish in vitro. Caries Res. 1980; 14: 315-323.

  18. Beltrán-Aguilar E, Goldstein J, Lockwood S. Fluoride varnishes a review of their clinical use, cariostatic mechanism, efficacy and safety. J Am Dent Assoc. 2000; 131: 589-596.

  19. Tecnical Reference. Standard classification of Japan No. 872790. Authorization No. (45AM) 18. Application for medical insurance, Review 2000.

  20. Yamaga R, Nishino M, Yoshida S, Yokomizo I. Diammine silver fluoride and its clinical application. J Osaka Univ Dent Sch. 1972; 12: 1-20.

  21. http://.www.midentistry.com/ag2.html

  22. Klein U, Kanellis M, Drake D. Effects of four anticaries agents on lesion depth progression in an in vitro caries model. Pediatr Dent. 1999; 21: 176-180.

  23. Tucker K, Adams M, Shaw L, Smith A. Human enamel as a substrate for in vitro acid dissolution studies: influence of tooth surface and morphology. Caries Res. 1998; 32 (2): 135-140.

  24. ten Cate J, Damen J, Buijs M. Inhibition of dentin demineralization by fluoride in vitro. Caries Res. 1998; 32 (2): 141-147.

  25. Itthagarun A, Wei S. Morphology of initial lesions of enamel treated with different commercial dentifrices using a pH cycling model: scanning electron microscopy observations. Int Den J. 1999; 49: 352-360.

  26. Ivancakova R, Hogan M, Harless J, Wefel J. Effect of fluoridated milk on progression of root surface lesions in vitro under pH cycling conditions. Caries Res. 2003; 37: 166-171.

  27. Damen J, Buijs M, ten Cate J. Fluoride-dependent formation of mineralized layers in bovine dentin during demineralization in vitro. Caries Res. 1998; 32 (6): 435-440.

  28. Mukai Y, Lagerweij M, ten Cate J. Effect of a solution with high fluoride concentration on remineralization of shallow and deep root surface caries in vitro. Caries Res. 2001; 35 (5): 317-324.

  29. Orth R, Pereira C, Aparecido J. A modified pH-cycling model to evaluate fluoride effect on enamel demineralization. Pesqui Odontol Bras. 2003; 17 (3): 241-246.

  30. Nelson DGA, Coote GE, Shariati M, Featherstone JDB. High resolution fluoride profiles of artificial in vitro lesions treated with fluoride dentifrices and mouthrinses during pH cycling conditions. Caries Res. 1992; 26 (4): 254-262.

  31. Seppa L, Leppanen T, Hausen H. Fluoride varnish versus acidulated phosphate fluoride gel: a 3-year clinical trial. Caries Res. 1995; 29 (5): 327-330.

  32. De la Cruz CD, Camacho GE, Castillo GL, Cervantes A, Sánchez BC. Resistencia al ataque ácido en esmalte dental humano antes y después de la aplicación tópica de tres agentes fluorados. ADM. 2001; 58 (1): 31-35.

  33. Chu CH, Lo ECM, Lin HC. Effectiveness of silver diamine fluoride and sodium fluoride varnish in arresting dentin caries in Chinese pre-school children. J Dent Research. 2002; 81 (11): 767-770.

  34. Yamaga R, Nishino M, Yoshida S, Yokomizo I. Diammine silver fluoride and its clinical application. J Osaka Univ Dent Sch. 1972; 12: 1-20.

  35. Gotjamanos T, Afonso F. Unacceptably high levels of fluoride in commercial preparations of silver fluoride. Australian Dent J. 1997; 42 (1): 52-53.




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