Duarte MJ, Verduzco PJ, Jiménez AJM, Lee-Eng CV, Romero FS, Espinosa LRF, Jiménez AMC, Graciela SR, Calvo CJ

Language: Spanish
References: 16
Page: 43-50
PDF size: 626.28 Kb.

ABSTRACT

Background: There is a very few information about the compliance with Surviving Sepsis Campaign (SSC) care bundles and their impact on patients outcome.
Objective: To determine the rate of compliance with 6-hour care bundle and the impact of the compliance on hospital mortality in patients with septic shock.
Material and method: A retrospective and observational study was performed on 77 patients’ clinical records with septic shock in critical care units at General Hospital Dr. Nicolas San Juan, Toluca, Estado de Mexico. We compared the rate of compliance with 6-hour SSC bundle care and the stability conservation between 7 to 24 hours with the hospital mortality between the compliant and the non-compliant groups. We applied odds ratio (OR) estimation to analyze the mortality on non-compliant groups.
Results: The general mortality was 32.4%. Abdominal was the most common source of infection (57.1%) followed by the chest (20.7%). The non-compliant group was 40.3%, and their mortality was 61.2%, with an OR calculated on 10.5 (95% CI 3.43-32.4; p‹0.05). The stability between the 7 to 24 hours was not achieved in 48.1%, with a mortality of 45.9% and we found an OR calculated on 3.4 (95% CI 1.23-9.32;p=0.015). An individual analysis showed that when urine output item was not achieved at 6 hours, we estimated an OR on 9.9 (95% CI 1.05-99.66; p=0.023).
Conclusion: Non-compliance with the 6-hours sepsis bundle was associated with a mortality rise and 10.5 more risk to die. The improvement of this sepsis care bundle, and the stability conservation between the 7th to 24th hours can improve survival rates in patients with severe sepsis and septic shock.

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