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ISSN 1025-0255 (Electronic)

2014, Number 1

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AMC 2014; 18 (1)

C-reactive protein as evolutionary evidence in patients with acute myocardial infarction

Casanova CG, Solís CI, Alafaro MY, González CJR, Piña NJC

Language: Spanish
References: 19
Page: 15-29
PDF size: 273.12 Kb.


ABSTRACT

Background: myocardial ischemia is nowadays one of the most serious health problems worldwide and among its clinical presentations the acute myocardial infarction is the one that has the greatest morbidity and mortality. The high concentrations of C-reactive protein indicate instability of patches and inflammation and may be interpreted as the most important predictive risk factor in the ischemic episode.
Objective: to evaluate the results of C-reactive protein as evolutionary evidence in patients with acute myocardial infarction.
Methods: an analytical, prospective observational study was carried out at Manuel Ascunce Domenech University Provincial Hospital of Camagüey. The universe was composed of 210 patients diagnosed with acute myocardial infarction; the sample consisted of 70 patients: 35 cases with the diagnosis of non-complicated acute myocardial infarction and 35 cases with the diagnosis of complicated acute myocardial infarction, their C-reactive protein levels were determined at the admission and discharge from hospital.
Results: in the analysis of the risk factors behavior, regarding complicated acute myocardial infarction and non-complicated acute myocardial infarction, it was observed that 32 patients with complicated acute myocardial infarction presented high C-reactive protein levels for a 91,42 %, followed by smoking, sedentary lifestyle, hypertension, and obesity. Besides, in the first determination made in patients with complicated acute myocardial infarction, the 94, 28 % of the cases presented high C-reactive protein levels; in the second one, in a 97, 14 % of the cases, the levels were also high. During the hospital stay of the patients with complicated acute myocardial infarction it was stated that in a 94, 28 % of them there was a relation between the high C-reactive protein levels and the clinical evolution of patients.
Conclusions: high C-reactive protein levels are a predictive factor in the favorable or unfavorable evolution of the patient with acute myocardial infarction.


REFERENCES

  1. Martínez Rodríguez I, Cabrera Compte RJ, Suárez Yanes E. Necesidad de una unidad de cuidados coronarios para el ingreso de pacientes con síndrome coronario agudo. MEDICIEGO [Internet]. 2011 [citado 13 Ago 2012];17(supl2):[aprox. 1 p.]. Disponible en: http://bvs.sld.cu/revistas/mciego/vol17_supl2_%202011/articulos/t-2.html 26

  2. López Pérez JE, Rubiera Jiménez R, Lara Negret A, González Mena M, Díaz Delgado M, Villafranca R, et al. Factores predictivos de mortalidad en pacientes con infarto agudo del miocardio con elevación del segmento ST. Rev Cubana Cardiol Cir Cardiovasc [Internet]. 2010 [citado 13 Dic 2012];16(14):[aprox. 1 p.]. Disponible en: http://bvs.sld.cu/revistas/car/vol16_4_10/car04410.pdf

  3. Ojeda Riquenes Y, Valdivia Álvarez E, Pardo Pérez L, Valenciano Rivero M. Cuantificación de niveles de proteína C reactiva. Un arma útil en la estratificación del riesgo en pacientes con síndromes coronarios agudos. Rev electrón [Internet]. 2007 [citado 19 Nov 2012];32(2):[aprox. 1 p.]. Disponible en: http://www.ltu.sld.cu/revista/index_files/articles/2007/abril-junio07/abril-junio07_8.htm

  4. Makrygiannis S, Ampartzidou O, Zairis M, Patsourakos N, Pitsavos C, Cokkinos D, et al. Prognostic usefulness of serial C-reactive protein measurements in ST-elevation acute myocardial infarction. Ame J Card [Internet]. 2013 Jan [cited 2013 Aug 2];111(1):[about. 1 p.]. Available from: http://web.ebscohost.com/ehost/pdfviewer/pdfviewer?vid=22 & sid=7dba5d56-619d-4de4-b6c1-f0a9b124e625%40sessionmgr15 & hid=10

  5. Ricalde Alcocer A, Soto López M, Reyes P, Mendoza G, Cruz P, Alexánderson Rosas E, et al. Determinación de actividad inflamatoria en pacientes con arteritis de Takayasu mediante tomografía por emisión de positrones (PET)g. Archivos De Cardiología De México [Internet]. 2010 Oct [citado 4 Mar 2013];80(4):[aprox. 1 p.]. Disponible en: http://new.medigraphic.com/cgi-bin/resumen.cgi?IDREVISTA=12 & IDARTICULO=27581 & IDPUBLICACION=2941

  6. Egido de los Ríos J. Biomarcadores en la medicina cardiovascular. Rev Espa de cardiología [Internet]. 2009 [citado 19 Nov 2012];62(6):[aprox. 1 p.]. Disponible en: http://dialnet.unirioja.es/servlet/articulo?codigo=2998701

  7. Nead KT, Zhou MJ, Caceres R, Sharp JS, Wehner MR, Olin JM, et al. Usefulness of the addition of beta-2-microglobulin, cystatin C and C-reactive protein to an established risk factors model to improve mortality risk prediction in patients undergoing coronary angiography. Ame J Card [Internet]. 2013 Mar [cited 2013 Jun 14];111(6):[about 1 p.]. Available from: http://web.ebscohost.com/ehost/pdfviewer/pdfviewer?sid=4c72f9d7-05ea-496b-a372-2665dc0b9d7d%40sessionmgr11 & vid=3 & hid=25

  8. Scirica BM, Sabatine MS, Jarolim P, Murphy SA, de Lemos JL, Braunwald E, et al. Assessment of multiple cardiac biomarkers in non-ST-segment elevation acute coronary syndromes: observations from the MERLIN-TIMI 36 trial. Eur Heart J [Internet]. 2011 Mar [cited 2012 Feb 14];32(6):[about 1 p.]. Available from: 27 http://web.ebscohost.com/ehost/pdfviewer/pdfviewer?sid=719a1fcb-a723-46c3-8ab6-7fa3a6b4098e % 40sessionmgr13 & vid=3 & hid=25

  9. Lim P, Moutereau S, Simon T, Gallet R, Probst V, Ferrieres J, et al. Usefulness of fetuin-A and C-reactive protein concentrations for prediction of outcome in acute coronary syndromes (from the French Registry of Acute ST-Elevation Non-ST-Elevation Myocardial Infarction [FAST-MI]). Ame J Card [Internet]. 2013 Jan [cited 2013 Aug 1];111(1):[about 1 p.]. Available from: http://web.ebscohost.com/ehost/pdfviewer/pdfviewer?vid=41 & sid=03b392c5-710d-4193-b5a2-0b910bbc473b%40sessionmgr11 & hid=25.

  10. Gu J, Hu W, Xiao H, Feng X, Chen Y, Zhang D. Intra-aortic balloon pump improves clinical prognosis and attenuates C-reactive protein level in acute STEMI complicated by cardiogenic shock. Cardiology [Internet]. 2010 [cited 2012 Nov 1];117(1):[about 1 p.]. Available from: http://www.karger.com/Article/Fulltext/319618

  11. Makrygiannis SS, Ampartzidou OS, Zairis MN, Patsourakos NG, Pitsavos C, Tousoulis D, et al. Prognostic useful ness of serial C-reactive protein measurements in ST-elevation acute myocardial infarction. Ame J Card [Internet]. 2013 Jan [cited 2013 Fef 27];111(1):[about 1 p.]. Available from: http://web.ebscohost.com/ehost/pdfviewer/pdfviewer?vid=22 & sid=7dba5d56-619d-4de4-b6c1-f0a9b124e625%40sessionmgr15

  12. Guerreiro Hernández AM, Villaescusa Blanco R, Morera Barrios LM, Castro Isaac M, Cruz Arencibia J. Evaluación de un método de aglutinación con látex para la detección de proteína C reactiva. Rev Cubana Hematol Inmunol Hemoter [Internet]. Abr 2009 [citado 12 Abr 2013];25(1):[aprox. 1 p.]. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext & pid=S0864-02892009000100008 & lng=es

  13. Rodríguez Navarro D, Rodríguez Acosta M, Alfonso Alfonso LE, Quintana Ruiz M, Catellanos Puerto E, Garcés Suárez Y. Alteraciones de la proteína C reactiva en los lesionados y su correlación con el TRISS. Rev Cub Med Mil [Internet]. Mar 2012 [citado 16 Abr 2013];41(1):[aprox. 1 p.]. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext & pid=S0138-65572012000100006 & lng=es.

  14. Pérez Oliva DJ, Martínez Piñeyro J, Gutiérrez García F, Raola ME, Benítez O. Proteina c reactiva elevada e hipoalbuminemia: sindrome/complejo malnutrición, microinflamación crónica, ateroesclerosis: significado pronostico en pacientes hemodializados. Rev Haban Cienc Méd [Internet]. 2009 [citado 12 Abr 2013];8(1):[aprox. 1 p.]. Disponible en: 28 http://scielo.sld.cu/scielo.php?script=sci_arttext & pid=S1729-519X2009000100023 & lng=es.

  15. La Greca RD. Potencialidad de los Biomarcadores de Inflamación en la detección precoz de la enfermedad cardiovascular. Revi Méd Clínica Condes [Internet]. 2012 Nov [citado 21 May 2013];23(6):[aprox. 1 p.]. Disponible en: http://web.ebscohost.com/ehost/pdfviewer/pdfviewer?vid=27 & sid=dd92e1ba-b801-4479-8a2f-25e482f1db21%40sessionmgr14 & hid=

  16. Ishikawa S, Kayaba K, Gotoh T, Nakamura Y, Kajii E. Metabolic syndrome and C-reactive protein in the general population: JMS cohort study. Circ J [Internet]. 2007 [cited 2010 Oct 11];71(1):[about 1 p.]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/17186974

  17. Shacham Y, Leshem Rubinow E, Ben Assa E, Rogowski O, Topilsky Y, Roth A, et al. Comparison of C-reactive protein and fibrinogen levels in patients having anterior wall ST-Segment elevation myocardial infarction with versus without left ventricular thrombus (from a primary percutaneous coronary intervention cohort). Ame J Card [Internet]. 2013 Jul [cited 2013 Oct 1];112(1):[about 1 p.]. Available from: http://web.ebscohost.com/ehost/pdfviewer/pdfviewer?sid=ee51df22-8f7a-4cd3-940f-b515050f14e3%40sessionmgr13 & vid=1 & hid=22

  18. Liu Y, Tan N, Zhou YL, Chen YY, Chen JY, Chen J, et al. High-sensitivity C-reactive protein predicts contrast-induced nephropathy after primary percutaneous coronary intervention. J Nephrol [Internet]. 2012 May [cited 2013 Oct 21];25(3):[about 1 p.]. Available from: http://web.ebscohost.com/ehost/pdfviewer/pdfviewer?sid=3db64f13-bdec-43b5-a565-c60e9444cd79%40sessionmgr13 & vid=1 & hid=10

  19. Akbarzadeh Najar R, Ghaderian S, Tabatabaei Panah A. C-reactive protein (CRP) gene polymorphisms: implication in CRP plasma levels and susceptibility to acute myocardial infarction. Molecular Biology Reports [Internet]. 2012 Apr [cited 2013 Oct 21];39(4):[about 1 p.]. Available from: http://web.ebscohost.com/ehost/pdfviewer/pdfviewer?sid=79fb81d8-71be-49c5-9384-e26690824172%40sessionmgr12 & vid=1 & hid=10




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