2013, Number 2
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Rev Hosp Jua Mex 2013; 80 (2)
Atosiban vs. orciprenalina en la amenaza de parto pretérmino
Jiménez-Huerta J, Alarcón-Alcántara MD, Flores-Méndez VM, Gutiérrez-Ramírez A
Language: Spanish
References: 17
Page: 115-120
PDF size: 212.93 Kb.
ABSTRACT
Introduction. The World Health Organization (WHO) defines preterm birth as birth before 37 weeks of gestation prematurity
being 69% of perinatal mortality and is considered the leading cause of infant death after the first month of life.
Objective.To compare orciprenaline and atosiban in the treatment of preterm labor in Hospital Juárez de México.
Material and methods.
Prospective, comparative clinical, integrating 56 patients between 28 and 34 weeks of gestation, with cervical and uterine activity
changes.
Results. The utero-inhibition atosiban was found in 92.9 patients, only 2 patients finding fault. Otherwise, metaproterenol
with a 66.7% success, with overall success difference between groups with p-value = 0.0325. The answer tocolytic atosiban is
independent of demographic variables of the patients and a higher incidence of cardiovascular events in the metaproterenol
group with p ≤ 0.0001.
Conclusions. Patients managed with atosiban immediate response to the drug was well tolerated, with
minimal adverse effects.
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