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2013, Number 4

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Rev Cubana Pediatr 2013; 85 (4)

Antiepileptic drug treatment for children

Pozo AAJ, Pozo LD

Language: Spanish
References: 102
Page: 497-516
PDF size: 114.88 Kb.


ABSTRACT

The objective of this paper was to make a literature review on the antiepileptic drug treatment for children. An important aspect of this type of treatment is to reduce or to cease epileptic crises in order to assure better quality of life. There are several factors that should be considered at the time of selecting the first antiepileptic drug such as relative efficacy, tolerability, drug interactions and long-term safety of the selected drug, type of seizure, epileptic syndrome, age, sex, weight, associated comorbidities and others. If one decides to use a combined treatment, then drugs having various mechanisms of action must be selected. The first-generation or classical antiepileptic drugs are all effective and continue playing an important role in the present treatment of epilepsy. These drugs are currently used as treatment of choice for many types of seizures or epileptic syndromes. Few second generation antiepileptic drugs are considered at present to be the first choice for the treatment of epilepsy in the child.


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