2013, Number 4
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Rev Cub Med Mil 2013; 42 (4)
Platelet count/spleen bipolar diameter ratio below 909 to predict oesophageal varices
Infante VM, Rosado VFC, Pérez LM, Samada SM, Hernández AM
Language: Spanish
References: 15
Page: 451-456
PDF size: 55.74 Kb.
ABSTRACT
Introduction: a platelet count/spleen bipolar diameter ratio below 909 is considered to be a good indicator of the presence of oesophageal varices.
Objective: carry out an external validation of the value of this ratio to diagnose oesophageal varices.
Methods: evaluation study of diagnostic tests of 102 cirrhotic patients of various causes, with a predominance of the male sex (55/102; 53.9 %) and a mean age of 55.76 ± 12.6. Determinations were based on laboratory variables, abdominal echography and upper endoscopy as a reference test. Sensitivity, specificity, predictive values and likelihood ratios were estimated to determine the accuracy of the ratio for the diagnosis of oesophageal varices.
Results: 65.7 % of the cases (n= 67) had oesophageal varices. The ratio showed a sensitivity of 96.30 % (CI 95 %: 87.32-100.00) with a negative predictive value of 97.1 % (CI 95 %: 90.19-100.00). Diagnostic accuracy was confirmed with ROC curve analysis (c= 0.927; CI 95 %: 0.873-0.980).
Conclusions: in the series it was possible to reproduce the results that consider the ratio under study to be a valuable method to identify the presence of oesophageal
varices in cirrhotic patients.
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