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ISSN 1025-0255 (Electronic)

2013, Number 6

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AMC 2013; 17 (6)

Prevalence, clinical forms and factors associated to congenital defects of the digestive system

Chávez VJÁ, Duarte CLM, García BC, Quiñones HJ, Castro GJE, Ramos WZR

Language: Spanish
References: 27
Page: 672-688
PDF size: 259.38 Kb.


ABSTRACT

Background: the digestive system is one of the most affected by congenital defects which constitute a global health problem since they are among the main causes of children’s mortality and are difficult to prevent.
Objective: to identify factors associated to the appearance of congenital defects of the digestive system and the magnitude of the risk that entails its presence in the municipality of Camaguey.
Methods: the study of cases and checksups with a universe composed of all the conceptions of the studied period. Of the population composed of 53 congenital defects, the sample was of 30 cases. The 30 checkups were of healthy children from the same health area, of the same sex and probable age for each case. The checkups were made from January, 2006 to January, 2011.
Results: the nervous system predominated over the congenital defects of the digestive system which were in the background fallowed by cardiopathies. Gastroschisis was the most frequent anomaly fallowed by diaphragmatic hernias, omphalocele, and esophageal atresia. Coffee consumption in the mother (p=0,002;OR:5,53;IC:1,031,14), the smoking habit in the father (p=0,009;OR:6,45;IC:1,5726,36), and previous cases of anomalies in the family (p=0,009;OR:6,40;CI:1,6025,66) were the factors that showed statistical association to the presence of congenital defects of the digestive system.
Conclusions: erratic frequencies that indicated the action of exogenous teratogens were not established; each identified independent factor increased in more than five times the provability of presenting congenital defects of the digestive system and its action would triple that number. The results suggest redirecting the project to the exhaustive exploration of the identified factors; subsequent studies with greater samples to get to clinical conclusions with more certitude, are recommended.


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