2013, Number 2
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Alerg Asma Inmunol Pediatr 2013; 22 (2)
Management of chronic rhinosinusitis in children
Sacre-Hazouri JA, Sacre GL, Rodríguez PN
Language: English
References: 76
Page: 61-69
PDF size: 194.95 Kb.
ABSTRACT
Chronic rhinosinusitis (CRS) in children and adults appear to have different etiology and therefore different diagnostic and treatment strategies. Adult chronic rhinosinusitis has a relatively greater inflammatory component whereas childhood chronic rhinosinusitis has a relatively greater infectious component. This is secondary to immaturity of the pediatric immune system, increased incidence of viral upper respiratory tract infections, smaller ostia of the sinuses and adenoidal hypertrophy. Concentrations of eosinophils in adult mucosa are greater than those in children. There is a greater degree of collagen deposition and expansion of submucosal mucous glands in the adult sinus indicating more tissue remodeling and potentially greater irreversible scarring. Immune deficiencies, cystic fibrosis, and ciliary dyskinesia are more likely to occur in children. Being a multifactorial disease careful history and physical examination, together with appropriate investigations are essential for the correct diagnosis and treatment.
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