2013, Number 2
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Alerg Asma Inmunol Pediatr 2013; 22 (2)
Current affairs in food allergy
Huerta HRE, Huerta LJG, Ortega MJA
Language: Spanish
References: 48
Page: 43-60
PDF size: 654.25 Kb.
ABSTRACT
More than 5 international guidelines in food allergy, with the aim of providing tools for optimal diagnosis and treatment to health personnel have been edited. Approximately 220 to 550 million people in the world have a food allergy, affecting the quality of life both in the patient and their families. The clinical picture is very varied, depending on the immunologic mechanism involved. Some patients have sensitization to multiple foods not taxonomically related, which panallergens play a decisive role. Panallergens are ubiquitous molecules in nature, with an essential role and whose structure has been maintained, sharing a high homology between different species, responsible for cross-reactivity between foods; among them are the profilins and the LTPs. The diagnosis is clinical, but also helping us with tests
in vitro and
in vivo for confirmation. Treatment consists of removing the diet food offender, in addition to other new therapies in clinical and preclinical phases; in patients under 2 years of age with CMPA and not fed with breast milk, it is suggested to use special formulas. There will be changes in the future in the recommendations on the early
versus late weaning. On the other hand changes in our way of life have contributed to the increase in allergic diseases. The exhaustive study of epigenetics and prenatal influence in asthma and allergic diseases is a priority to generate measures of prevention as well as collaboration between health personnel and the appropriate authorities.
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