2013, Number 1
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Arch Neurocien 2013; 18 (1)
The use of magnesium sulfate in subarachnoid hemorrhage due to aneurysmal bleeding to prevent vasospasm
Ramírez-Barrios LR, Martínez-Ponce LÁ, Pérez-Cárdenas S, Guevara-Soria V
Language: Spanish
References: 10
Page: 39-41
PDF size: 96.74 Kb.
ABSTRACT
Objective: to determine the effectiveness of magnesium sulfate therapy for prevention of vasospasm in patients
with subarachnoid hemorrhage from aneurismal rupture.
Material and methods: twenty patients were included with
subarachnoid hemorrhage from aneurismal rupture. The level of consciousness by the Glasgow Coma Scale, Fisher
scale, Hunt & Hess scale were done and followed. The patients were split in two groups, one was given magnesium
sulfated and triple H therapy and the second one only triple H therapy. The statistical analyze was done using Central
tendency binary logistic regression and X
2.
Results: 15% of patients had neurological sequels at 21 days after the
SAH, 10% died, of whom 50% had vasospasm. The presence of vasospasm differs in patients treated with magnesium
sulfate, and was calculated by X
2, but had no significant association (p = 0.383).
Conclusions: treatment with
magnesium sulfate in patients with SAH, does not help preventing neurological deterioration caused by vasospasm
and had the same outcome as dose with no magnesium sulfate. This suggests that a study with more subjects is
needed. Patients with lower fishers II or less had fewer complications.
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