2013, Number 6
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Acta Pediatr Mex 2013; 34 (6)
Use of gammaglobulin in transplantation of hematopoietic stem cells and in kidney transplant
Ruíz-Morales JA, Cruz-Medina CS, Pérez-García M, Campos-Gutiérrez MÁ, del Campo-Martínez M, Olaya-Vargas A
Language: Spanish
References: 25
Page: 348-352
PDF size: 353.42 Kb.
ABSTRACT
Intravenous immunoglobulin (IVIG) preparation comprise a pooled
IgG antiboidies from the serum of thousands of donors and has
been used as therapy in several pathologies such as: primary immunodeficiency’s,
autoimmune diseases, Kawasaki disease and on
transplantation field to treat graft versus host disease, viral infections
and sensitization due to anti-donor antibodies. The anti-donor
antibodies are an important risk factor for acute humoral rejections
on kidney transplantation and are a very important risk factor for
graft failure after hematopoietic stem cell transplantation. Using IVIG
to treat patients with anti-donor antibodies might reduced the risk
of acute kidney rejection and graft failure following hematopoietic
stem cell transplantation
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