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2013, Number 1

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Med Sur 2013; 20 (1)

Volumen plaquetario medio. Su significado en la práctica clínica

Carrillo-Esper R, Carrillo-Córdova DM, Carrillo-Córdova CA, Carrillo-Córdova LD

Language: Spanish
References: 38
Page: 17-20
PDF size: 98.39 Kb.


ABSTRACT

Platelets have a role in coagulation, thrombosis, immunity, inflammation and angiogenesis. It has been shown that platelet size, when measured as mean platelet volume (MPV), is a marker of platelet function and is associated with platelet activity. Evidence derived from several studies and meta-analysis suggests a correlation between MPV increased and the risk of thrombosis and inflammation. Elevated MPV is potentially a useful prognostic biomarker in patients with cardiovascular disease, diabetes mellitus, metabolic syndrome, several inflammatory and prothrombotic conditions. The elevation of the MPV is highly correlated with the presentation and poor prognosis of acute myocardial infarction and coronary restenosis after placement of stents. The aim of this paper is to review the evidence relating to the implementation of MPV as a marker of different proinflammatory and prothrombotic diseases


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