Carrillo-Esper R, Carrillo-Córdova DM, Carrillo-Córdova CA, Carrillo-Córdova LD

Idioma: Español
Referencias bibliográficas: 38
Paginas: 17-20
Archivo PDF: 98.39 Kb.

RESUMEN

Las plaquetas son fundamentales en los procesos de coagulación, trombosis, inmunidad, inflamación y angiogénesis. El tamaño de la plaqueta, evaluado mediante el volumen plaquetario medio (VPM), es un marcador de la función y actividad plaquetaria. Evidencia derivada de estudios clínicos y metaanálisis sugieren una correlación entre el incremento en el VPM y el riesgo de trombosis e inflamación. Un VPM elevado es un potencial biomarcador en enfermedad cardiovascular, diabetes mellitus, síndrome metabólico y diversas entidades proinflamatorias y protrombóticas. La elevación del VPM tiene una estrecha correlación con la presentación y mal pronóstico del infarto agudo del miocardio y reestenosis de las coronarias posterior a la colocación de Stents. El objetivo de este trabajo es revisar la evidencia relacionada con la implementación del VPM como marcador de diferentes enfermedades proinflamatorias y protrombóticas.

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