2013, Number 4
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Perinatol Reprod Hum 2013; 27 (4)
Utility of the cellular surface markers in the diagnosis of neonatal sepsis. Preliminary report
Vázquez-Rodríguez S, González-Jiménez MA, Hidalgo-Aparicio B, Paredes-Vivas Y, Cérbulo-Vázquez A
Language: Spanish
References: 15
Page: 243-247
PDF size: 269.16 Kb.
ABSTRACT
Quantification of leukocyte populations in peripheral blood can be performed using flow cytometry. The leukocyte populations are often contrasted between neonate and adult peripheral blood. This preliminary report shows the analysis of three samples of umbilical cord blood of healthy subjects and three peripheral blood samples of newborns diagnosed with late sepsis. Our results show that CD69, CD71 and CD45RO could be useful to differentiate states of sepsis in neonates. We propose a subsequent study to generate a multiparametric flow cytometry analysis that will allow a comprehensive analysis of neonatal sepsis.
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