2013, Número 4
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Perinatol Reprod Hum 2013; 27 (4)
Análisis de marcadores de superficie celular de utilidad en el diagnóstico de la sepsis neonatal. Reporte preliminar
Vázquez-Rodríguez S, González-Jiménez MA, Hidalgo-Aparicio B, Paredes-Vivas Y, Cérbulo-Vázquez A
Idioma: Español
Referencias bibliográficas: 15
Paginas: 243-247
Archivo PDF: 269.16 Kb.
RESUMEN
La cuantificación de poblaciones leucocitarias en sangre periférica puede realizarse con ayuda del análisis por citometría de flujo. Los valores de poblaciones leucocitarias en neonatos son frecuentemente contrastados con sangre periférica de adultos. El presente reporte preliminar muestra el análisis de tres muestras de sangre de cordón umbilical de pacientes sanos y tres muestras de sangre periférica de neonatos con diagnóstico de sepsis tardía. Los resultados obtenidos muestran que CD69, CD71 y CD45RO pueden ser de utilidad para diferenciar estados de sepsis en neonatos. En un estudio futuro, la propuesta es realizar un análisis multiparamétrico por citometría de flujo que permita un análisis integral de la sepsis neonatal.
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