2013, Number 1
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Arch Inv Mat Inf 2013; 5 (1)
Sensibilidad y especificidad de la detección cualitativa de β-HCGh en el lavado cervicovaginal para el diagnóstico de ruptura prematura de membranas
Aguilar BLR, Rodríguez AG, Pardo MRV
Language: Spanish
References: 16
Page: 41-46
PDF size: 148.85 Kb.
ABSTRACT
Introduction: Premature rupture of membranes is a common issue in obstetrics, sometimes the diagnosis is uncertain, and the detection of human chorionic gonadotropin in cervicovaginal lavage has proved to be useful in the diagnosis.
Objective: To determine the sensitivity and specificity of qualitative concentration of human chorionic gonadotropin in cervicovaginal lavage for the diagnosis of premature rupture of membranes.
Material and methods: A diagnostic test was performed in 100 pregnant women 20 weeks and older, who reported premature rupture of membranes. The diagnosis was established by clinical examination and crystallography, USG ILA measurement, and monitoring until resolution of pregnancy. All patients underwent cervicovaginal lavage fluid obtained and human chorionic gonadotropin was determined with a rapid qualitative test (sensitivity 200 mUI/mL). We calculate the sensitivity, specificity and positive predictive values and negative diagnostic test.
Results: In 59 patients confirmed the rupture of membranes and at 41 was discarded, the average gestational age was 37.14 ± 3.83 weeks in patients with ruptured and 34.71 ± 5.26 weeks in patients without rupture. The sensitivity was 96.6%, specificity of 100%, the predictive value positive 100%, and negative 95.34%.
Conclusion: The determination qualitative of gonadotropin chorionic human in the washing cervicovaginal is useful to establish the diagnosis of rupture premature membrane.
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