2013, Number 10
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Ginecol Obstet Mex 2013; 81 (10)
VVF: laparoscopic versus open surgical abdominal
Tovar-Rodríguez JM, Medel-Lagunes IC, Acosta-Altamirano G, Vargas-Hernández VM
Language: Spanish
References: 42
Page: 578-586
PDF size: 179.57 Kb.
ABSTRACT
Background: The molar pregnancy is complicated with hypertension
before 20 weeks, divided into complete mole and
partial mole, and in diploid and triploid hydatidiform mola
depending on the fetal chromosomes.
Objective: To determine clinical and laboratory characteristics
of patients with hydatidiform mole with and without
hypertension, and choriocarcinoma, correlate serum chorionic
gonadotropin (hCG) and hypertension.
Material and methods: We reviewed 55 cases with histopathologically
proven mole, separately analyzed clinical,
laboratory and hCG.
Results: The prevalence of mole with hypertension was 1:7;
with the choriocarcinoma is 1:11. The age and sexual initiation
of mole with hypertension was higher (p =. 004 and .002
respectively), liver transaminase AST (p =. 004) and lactate
dehydrogenase are higher in the group with hypertension
(p =. 000). Positive correlation was obtained r = .246 p =. 044
statistically significant between mean arterial pressure and
hCG. We reviewed 31 cases of 28 national and international
articles, in patients with diploid hydatidiform the product is
allowed to live normal and high blood pressure is showing
mild preeclampsia, while partial moles are triploid, malformed
products, incompatible with life and with hypertension severe
like severe pre-eclampsia.
Conclusions: The molar pregnancy is partially diagnosed with
hypertension in our environment, is not properly analyzed and
that most of the products of curettage were not performed
genetic testing. The hCG probably participate in the hypertensive
disorders of pregnancy.
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