2013, Number 2
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Evid Med Invest Salud 2013; 6 (2)
Hemoptysis and dysphonia: Unusual description in Pancoast syndrome
García O, Vale OMA, Cortés TA
Language: Spanish
References: 19
Page: 59-62
PDF size: 294.46 Kb.
ABSTRACT
Pancoast syndrome features a series of signs and symptoms by compression of surrounding structures secondary to tumors located in the pulmonary apex. Up to 50% of cases is associated with Horner Syndrome. The primary etiology is are malignant tumors. Initial symptoms include pain at the shoulder and arm, and also ptosis miosis and anhidrosis; however, rarely occur dysphonia or hemoptysis, aspect associated with advanced stages of cancer diseases. The diagnosis is supported by clinical analysis, X-ray imaging and confirmed by pathology study. The outcome is based on the TNM International Classification System. Advanced stages have a poor survival rate, at 5 years between 5 and 15% of cases.
REFERENCES
Arcasoy SM, Jett JR. Superior pulmonary sulcus tumors and Pancoast’s syndrome. N Engl J Med. 1997; 337: 1370-1376.
Jett JR. Superior sulcus tumors and Pancoast’s syndrome. Lung Cancer. 2003; 42: S17-S21.
Pancoast HK. Importance of careful roentgen-ray investigations of apical chest tumors. JAMA. 1924; 83: 1407-1411.
Pancoast H. Superior pulmonary sulcus tumor: tumor characterized by pain, Horner’s syndrome, destruction of bone and atrophy of hand muscles. JAMA. 1932; 99: 1391-1396.
Kong YX, Wright G, Pesudovs K, O’Day J, Wainer Z, Weisinger HS. Horner syndrome. Clin Exp Optom. 2007; 90: 336-344.
George A, Haydar AA, Adams WM. Imaging of Horner’s syndrome. Clin Radiol. 2008; 63: 499-505.
Bidwell J, Pachner R. Hemoptysis: diagnosis and management. Am Fam Physician. 2005; 72: 1253-1260.
Hirshberg B, Biran I, Glazer M, Kramer MR. Hemoptysis: etiology, evaluation, and outcome in a tertiary referral hospital. Chest. 1997; 112: 440-444.
Schwartz SR, Cohen SM, Dailey SH, Rosenfeld RM, Deutsch ES, Gillespie MB et al. Clinical practice guideline: hoarseness (dysphonia). Otolaryngol Head Neck Surg. 2009; 141 (3 Suppl 2): S1-S31.
Komaki R, Roth JA, Walsh GL, Putnam JB, Vaporciyan A, Lee JS et al. Outcome predictors for 143 patients with superior sulcus tumors treated by multidisciplinary approach at the University of Texas MD Anderson Cancer Center. Int J Radiat Oncol Biol Phys. 2000; 48: 347-354.
Hagan MP, Choi NC, Mathisen DJ, Wain JC, Wright CD, Grillo HC. Superior sulcus lung tumors: impact of local control on survival. J Thorac Cardiovasc Surg. 1999; 117: 1086-1094.
Hatton MQ, Allen MB, Cooke NJ. Pancoast syndrome: an unusual presentation of adenoid cystic carcinoma. Eur Respir J. 1993; 6: 271-272.
Montero C, Deben G, de la Torre M, Álvarez A, Verea H. Síndrome de Pancoast e infiltración tumoral como primera manifestación de un linfoma de Hodking. Arch Bronconeumol. 2004; 40 (6): 287-289.
White HD, White BA, Boethel C, Arroliga AC. Pancoast’s syndrome secondary to infectious etiologies: a not so uncommon occurrence. Am J Med Sci. 2011; 341: 333-336.
Gibney RT, Connolly TP. Pulmonary amyloid nodule simulating Pancoast tumor. J Can Assoc Radiol. 1984; 35: 90-91.
Heelan RT, Demas BE, Caravelli JF. Superior sulcus tumors: CT and MR imaging. Radiology. 1989; 170: 637-641.
Maxfield RA, Aranda CP. The role of fiberoptic bronchoscopy and transbronchial biopsy in the diagnosis of Pancoast’s tumor. N Y State J Med. 1987; 87: 326-329.
Detterbeck FC, Boffa DJ, Tanoue LT. The new lung cancer staging system. Chest. 2009; 136: 260-271.
Rusch VW. Management of Pancoast tumours. Lancet Oncol. 2006; 7: 997-1005.