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Colegio de Medicina Interna de México.

2013, Number 5

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Med Int Mex 2013; 29 (5)

Chronic Periodontitis: A Cardiovascular Risk Factor?

Fonseca-Reyes S

Language: Spanish
References: 54
Page: 495-503
PDF size: 233.78 Kb.


ABSTRACT

Periodontitis is a family of diseases that affect structures supporting the teeth caused by infections sustained by periodontal pathogens such as Porphyromonas gingivalis, Treponema denticola, Aggregatibacter actinomycetemcomitans, Tannerela forsythia, Prevotella intermedia which lead to soft and hard tissue destruction, dental mobility, and over time the loss of dental pieces. Evidence from observational epidemiologic studies suggests that periodontal disease is independently associated with atherosclerotic vascular disease. Despite the fact that the strength of association is still modest, the findings cannot be ascribed solely to the effects of confounders. There is evidence to support the plausibility of the relation and have even outlined some of the pathophysiological pathways. These mechanisms include systemic inflammation, molecular mimicry, bacteremia and vascular infection by periodontal pathogens. The relation between periodontitis and atherosclerosis has great relevance, given the high incidence of both disorders, elevated cost to society and potential impact on public health.


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