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2013, Number 4

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AMC 2013; 17 (4)

Relation between condylomata acuminata and penis cancer and anus cancer

Ferrá TTM, Ramírez VEN

Language: Spanish
References: 27
Page:
PDF size: 90.34 Kb.


ABSTRACT

Background: there are 200 genotypes of human papillomaviruses, more than 40 of them have isolated in the lower genital tract. They are subclassified according to the oncogenic capacity in low-risk and high-risk. The clinical manifestation is condylomata acuminata that are generally caused by low-risk human papillomaviruses but constitute an important indicator of infection by high-risk viruses. Infection caused by this virus has been proved in the penis and anus squamous carcinoma.
Objective: to determine the relation between condylomata acuminata and penis cancer and anus cancer.
Methods: a cross-sectional, descriptive, observational study was conducted. The universe was composed of all the patients with condylomata acuminata that assisted to the consultations of Dermatology and Urology of the Manuel Ascunce Domenech University Hospital of Camagüey, from January 1st to December 31st, 2011. For the subclinical detection of condylomata acuminata, 5 % acetic acid was applied; urethral cytology was made to all the patients who presented lesions in the penis and anal cytology in those patients with lesions in the anus. Penis biopsy and ureteroscopy was made to the patients that presented urethral cytology with suspicions of neoplastic cells; anus biopsy and anoscopy was made to those patients whose anal cytology showed suspicions of neoplastic cells. The information obtained was processed through the statistical program SPSS-10. The method applied was the descriptive statistics of distribution of absolute and relative frequencies. The results of the study were showed in tables.
Conclusions: the greatest incidence of condylomata acuminata was found in patients who were from 15 to 19 years old. Association with subclinical forms was observed in more than the tenth part of them. Of the organ cytologies, the fifth part showed suspicions of the presence of neoplastic cells. None of the histopathological results was compatible with penis cancer or anus cancer. Ureteroscopy and anoscopy showed normal results.


REFERENCES

  1. Foldvari M. HPV infections: can they be eradicated using nanotechnology? Nanomedicine. 2012 Feb;8(2):131-5.

  2. Braillard Poccard PM, Braverman A, Cabrera MN, Chapier VV. Cáncer de cérvix: incidencia según edad y estadio tumoral. Rev Postg Vía Cated Med [Internet]. 2005 [citado 12 Jul 2012];(141):[aprox. 5 p.]. Disponible en: http://med.unne.edu.ar/revista/revista141/3_141.htm

  3. Yanofsky VR, Patel RV, Goldenberg G. Genital warts: a comprehensive review. J Clin Aesthet Dermatol. 2012 Jun;5(6):25-36.

  4. Sánchez-Vargas LO, Díaz Hernández C, Martínez Martínez A. Detection of Human Papilloma Virus (HPV) in oral mucosa of women with cervical lesions and their relation to oral sex practices. Inf Agents Canc. 2010;5:25.

  5. Stanley M. HPV: immune response to infection and vaccination. Infectious Agents and Cancer [Internet]. 2010 [cited 2012 Jul12];5:[about 19 p.]. Available from: http://www.infectagentscancer.com/content/5/1/19

  6. Zhang D, Zhang Q, Zhou L, Huo L, Zhang Y, Shen Z, et al. Comparison of prevalence, viral load, physical status and expression of humanpapillomavirus-16, -18 and -58 in esophageal and cervical cancer: a case-control study. BMC Cancer. 2010;10:650.

  7. Giraldi G, De Luca d'Alessandro E. The HPV infection in males: an update. Ann Ig. 2012 Nov-Dec;24(6):497-506.

  8. Álvarez Ramírez R. Detección del Virus del Papiloma Humano en Hombres Mediante Citología de Raspado Uretral utilizando la Citología en Fase Líquida. GEOSALUD [Internet]. 2005 [citado 9 Nov 2005];3(2):[aprox. 5 p.]. Disponible en: http://geosalud .com/VPH/index%20VPH.htm

  9. Lantero Abreu MI, Torres Peña R, Joanes Fiol J, Alonso Gómez ME, Abreu Daniel A, Lobio Cárdenas Z, et al. Infecciones de transmisión sexual. Pautas para su tratamiento. La Habana: MINSAP; 2004.

  10. Ramamoorthy S, Tsueng Liu-Y, Luo L, Miyai K, Lu K, Carethers JM. Detection of Multiple Human Papillomavirus Genotypes in Anal Carcinoma. Inf Agents Canc. 2010;5:17.

  11. Leval A, Herweijer E, Arnheim-Dahlstrom L, Walum H, Frans E, Sparen P, et al. Incidence of genital warts in Sweden before and after quadrivalent human papillomavirus vaccine availability. J Infect Dis. 2012 Sep 15;206(6):860-6.

  12. Kresge KJ. Cervical cancer vaccines: introduction of vaccines that prevent cervical cancer and genital warts may fore-shadow implementation and acceptability issues for a future AIDS vaccine. /AV/ Rep [Internet]. 2005 [citado 9 Mar 2008];9(5):[aprox. 9 p.]. Disponible en: http://www.aegis.org/pubs/IAVI/2005/IAVI0511-01-EN.htm/

  13. Dinh TH, Sternberg M, Dunne EF, Markowitz LE.Genital warts among 18- to 59-year-olds in the United States, national health and nutrition examination survey, 1999--2004. Sex Transm Dis. 2008;35(4):357-60.

  14. Gross G, Pfister H. Role of human papillomavirus in penile cancer, penile intraepithelial squamous. Med Microbiol Immunol. 2004 Feb;193(1):35-44.

  15. Ferrá Torres TM, Amador Díaz ME. Algunos aspectos epidemiológicos de los condilomas acuminados. Estudio de 307 casos. Arch Med Camagüey [Internet]. 2008 [citado 12 Ene 2009];12(3):[aprox. 13 p.]. Disponible en: http://www.cmw.sld.cu/amc/v12n3-2/567.htm

  16. Rodríguez García Y, Oliva Díaz JA, Gil Hernández A. La sexualidad en los adolescentes: Algunas consideraciones. Arch Méd Camagüey. [Internet]. 2007 [citado 12 May 2012];11(1):[aprox. 13 p.]. Disponible en: http://www.cmw.sld.cu/amc/v11n1-2/567.htm

  17. Vidal Valdés M, Vidal Valdés M, Barrios Rodríguez JA, González Sánchez K. Algunos aspectos sobre sexualidad en adolescentes de una secundaria básica del municipio Jaruco. Rev Ciencias Médicas La Habana. 2011;17(1):23-45.

  18. Merconchini García D. Comportamiento del condiloma venéreo en la Policlínica 28 de septiembre de enero a junio del 2008. Rev Elect Facultad de Ciencias Médicas de Las Tunas. 2009;14(3):2-3.

  19. Giuliano AR. Human papillomavirus vaccination in males. Gyneco Oncol. 2007 Nov;107(2 Suppl):24-6.

  20. Satyaprakash AK, Tyring SK. Human papillomaviruses vaccine: a dermatologic perspective. Indian J Dermatol Venereol Leprol. 2010 Jan-Feb;76(1):14-9.

  21. Chow LT, Broker TR. Human Papillomavirus Infections: Warts or Cancer? Cold Spring Harb Perspect Biol. 2013 Jul 1;5(7):45-9.

  22. Saibishkumar EP, Crook J, Sweet J. Neonatal circumcision and invasive squamous cell carcinoma of the penis: a report of 3 cases and a review of the literature. Can Urol Assoc J. Feb 2008;2(1):39-42.

  23. Dona MG, Benevolo M, Vocaturo A, Palamara G, Latini A, Giglio A, et al. Anal cytological abnormalities and epidemiological correlates among men who have sex with men at risk for HIV-1 infection. BMC Cancer. 2012;12:476.

  24. Echenique I, Phillips BR. Anal warts and anal intradermal neoplasia. Clin Colon Rectal Surg. 2011 Mar;24(1):31-8.

  25. Hernández BY, Barnholtz-Sloan J, German RR, Giuliano AR, Goodman MT, King JB, et al. Burden of invasive squamous cell carcinoma of the penis in the United States, 1998–2003. Cancer. 2008;113(S10):2883-91.

  26. Blomberg M, Friis S, Munk C, Bautz A , Kjaer SK. Genital warts and risk of cancer: a Danish study of nearly 50 000 patients with genital warts. J Infect Dis. 2012 May 15;205(10):1544-53.

  27. Macaya A, Munoz-Santos C, Balaguer A, Barbera MJ. Interventions for anal canal intraepithelial neoplasia. Cochrane Database Syst Rev. 2012;12:CD009244




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