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2013, Number 3

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Rev Cubana Plant Med 2013; 18 (3)

Bioprospecting of Lacmellea standleyi fruits (lechemiel)

Soto CEL, Chicué AM, Murillo PE, Méndez AJJ

Language: English
References: 46
Page: 412-430
PDF size: 246.80 Kb.


ABSTRACT

Introduction: the idea to explore at least some of the regions diversity such as the Colombian Orinoco through bioprospecting study of Lacmellea standleyi (Woodson) Monach. arises as a consequence of ignorance of much of the floristic richness in Colombia and the potential relevance of much of this in the nutrition, health and industry.
Objective: to evaluate the antioxidant potential, nutritional and phenolic content, antimicrobial activity, and safety degree of aqueous, ethanol, and ethyl acetate extracts of Lacmellea standleyi fruits in three different ripening stages.
Methods: the nutritional value was evaluated using standardized methods to full fruit in its three ripening stages. Each of the extracts was chemically characterized by spectrophotometric assays. Antimicrobial activity was measured by the size of inhibition against strains of Staphylococcus aureus, Escherichia coli, and Candida parpsilosis; the acute toxicity of the fruits was measured through in vitro tests using Artemia salina as experimental model.
Results: the results show that green fruits are suppliers of antioxidant compounds. Higher levels of nutrients are found in the intermediate state and mature fruit has attractive organoleptic properties and a relatively high nutrient content.
Conclusions: the antioxidant capacity of Lacmellea standleyi fruits was evident in the three ripening stages, giving the plant a promising future in the pharmaceutical industry, standing out in this field the fruits in the green stage. Furthermore, the results suggest the application of the intermediate and mature fruits in the finished products development. The safety observed in the plant material warrants its use in human consumption.


REFERENCES

  1. Hait W, Rubin E, Alli E, Goodin S. Tubulin targeting agents. Review. Update on cancer therapeutics. 2007;54(2):1-18.

  2. Zenk M, Juenger M. Review, Evolution and current status of the phytochemistry of nitrogenous compounds. Phytochemistry. 2007;68(22-24):2757-72.

  3. Moura CF, Alves RE, Filgueiras HA, Araújo NC, Almeida AS. Quality of fruits native to latin-america for processing: mangaba (hancornia speciosa Gomes). ISHS Acta Horticulturae. 2002;575(1):549-54.

  4. Van Wyk BE. The potential of South African plants in the development of new food and beverage products. South African J Botany. 2011;77(4):857-68.

  5. Sampaio TS, Nogueira PC. Volatile components of mangaba fruit (Hancornia speciosa Gomes) at three stages of maturity. Food Chemistry. 2006;95(4):606-10.

  6. Mousinho KC, Oliveira CC, Ferreira JR, Carvalho AA, Magalhães H, Bezerra D, et al. Antitumor effect of laticifer proteins of Himatanthus drasticus(Mart.) Plumel-Apocynaceae. J Ethnopharmacol. 2011;137(1):421-6.

  7. Lumpu SN, Lutete GT, Kabangu K, Kanyanga RC, Apers S, Pieters L, et al. Assessment of the antidiarrhoeal properties of the aqueous extract, the 80 % methanol extract and its soluble fractions of the leaves of Alstonia congensis Engl. (Apocynaceae) in Wistar rats. J Ethnopharmacol. 2012;142(3):620-6.

  8. Lasisi AA, Olayiwola MA, Balogun SA, Akinloye OA, Ojo DA. Phytochemical composition, cytotoxicity and in vitro antiplasmodial activity of fractions from Alafia barteri olive (Hook F. Icon)-Apocynaceae. J Saudi Chemical Society. 2012 [cited Oct 2012]. Available at: http://www.sciencedirect.com/science/article/pii/S1319610312000580

  9. Mendonça PM, Lima MG, Albuquerque LR, Carvalho MG, Queiroz MG. Effects of latex from «Amapazeiro» Parahancornia amapa (Apocynaceae) on blowfly Chrysomya megacephala (Diptera: Calliphoridae) post-embryonic development. Veterinary Parasitology. 2011;178(3-4):379-82.

  10. Marcano D, Hasegawa M. Fitoquímica Orgánica. 2da ed. Publicación del Consejo de Desarrollo Científico y Humanístico de la Universidad Central de Venezuela (Colección Estudios); 2002, p. 588 ISBN 980-00-2066-7.

  11. AOAC. Official Methods of Analysis of AOAC (Association of Official Analytical Chemists) International (18th ed.). AOAC International, Gaithersburg, MD; 2005.

  12. Englberger L, Schierle J, Hofmann P, Lorens A, Albert K, Levendusky A, et al. Carotenoid and vitamin content of Micronesian atoll foods: Pandanus (Pandanus tectorius) and garlic pear (Crataeva speciosa) fruit. J Food Composition Analysis. 2009;22(1):1-8.

  13. Booth SL, Sadowski JA. Determination of phylloquinone in foods by high-performance liquid chromatography. Methods Enzymol. 1997;282(1):446-56.

  14. Peterson JW, Muzzey KL, Haytowitz D, Exler J, Lemar L, Booth SL. Phylloquinone (vitamin K-1) and dihdyrophylloquinone content of fats and oils. J Food Composition Analysis. 2002;79(7):641-6.

  15. Singleton VL, Rossi JA. Colorimetry of total phenolics with phosphomolybdicphosphotungstic acid reagents. Am J Enology Viticulture. 1995;16(3):144-58.

  16. Re R, Pellegrinni N, Proteggente A, Pannala A, Yang M, Rice-Evans C. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Biol Med. 1999;26(9-10):1231-7.

  17. Brand-Williams W, Cuvelier ME, Berset C. Use of a free radical method to evaluate antioxidant activity. LWT Food Science Technology. 1995;28(1):25-30.

  18. Prieto P, Pineda M, Aguilar M. Spectrophotometric quantitation of antioxidant capacity through the formation of a phosphomolybdenum complex: specific application to the determination of vitamin E. Analytical Biochemistry. 1999;269(2):337-41.

  19. Mohamed R, Pineda M, Aguilar M. Antioxidant capacity of extracts from wild and crop plants of the Mediterranean region. J Food Science. 2007;72(1):S059-63.

  20. Mcgawa LJ, Steenkamp V, Eloff JN. Evaluation of Athrixia bush tea for cytotoxicity, antioxidant activity, caffeine content and presence of pyrrolizidine alkaloids. J Ethnopharmacol. 2007;110(1):16-22.

  21. Sanchez BS. Caracterización fisicoquímica y funcional de la fibra dietética del fruto del níspero (Eriobotrya japonica) y de la cáscara de mango obo (Mangifera indica L). [Tesis de Ingeniería de Alimentos]. Oaxaca: Instituto de Agroindustrias, Universidad Tecnológica de la Mixteca (UTM); 2005. 76 p.

  22. Salazar DM. Minerales. In: Micronutrientes. Cap. 3. Argentina: El Cid Editor; 2009. p. 22-32.

  23. Gallego SP, Riaño CE, Orozco L. Determinación del comportamiento químico y fisiológico de Feijoa sellowiana en almacenamiento. Rev Cenicafe. 2003;54(1):50-62.

  24. Mbeunkui F, Grace MH, Lila MA. Isolation and structural elucidation of indole alkaloids from Geissospermum vellosii by mass spectrometry. J Chromatography B. 2012;885-886:83-9.

  25. GuoHong-Ping LL, Di YT, Li SF, Cheng YY, Yang W, Li Y, et al. Indole alkaloids from Ervatamia chinensis. Phytochemistry. 2012;74(1):140-5.

  26. Flaubert M, Grace MH, Lategan C, Smith PJ, Raskin I, Lila MA. In vitro antiplasmodial activity of indole alkaloids from the stem bark of Geissospermum vellosii. J Ethnopharmacol. 2012;139(2):471-7.

  27. Tanaka CA, da Silva CC, Ferreira ICP, Machado GMC, Leon LL, de Oliveira AJB. Antileishmanial activity of indole alkaloids from Aspidosperma ramiflorum. Phytomedicine. 2007;14(6):377-80.

  28. Woodson RE. Studies in the Apocynaceae I (a critical study of the Apocynoidea, with special reference to genus Apocynum). Annals Missouri Botanical Garden. 1930;17(1-2):1-83.

  29. Juárez V, Alvarado L, Villaseñor JL. The family Apocynaceae sensu lato in Mexico: diversity and distribution. Rev Mexicana Biodiversidad. 2007;78(2):459-82.

  30. Queiroz C, Ribeiro A, Mendes M, Fialho E, Valente-Mesquita V. Polyphenol oxidase activity, phenolic acid composition and browning in cashew apple (Anacardium occidentale L.) after processing. Food Chemistry. 2011;125(1):128-32.

  31. Rastegar S, Rahemi M, Baghizadeh A, Gholami M. Enzyme activity and biochemical changes of three date palm cultivars with different softening pattern during ripening. Food Chemistry. 2012;134(3):1279-86.

  32. Singh SP, Singh Z, Swinny EE. Climacteric level during fruit ripening inûuences lipid peroxidation and enzymatic and non-enzymatic antioxidative systems in Japanese plums (Prunus salicina Lindell). Postharvest Biology Technology. 2012;65(1):22-32.

  33. Shi Y, Yao S, Jia Z, Lin N, Zheng R. Dietary phytophenols act as scavengers of reducing radicals. Food Chemistry. 2011;124(4):1322-7.

  34. Floegel A, Kimb DO, Chung SJ, Koo SI, Chun OK. Comparison of ABTS/DPPH assays to measure antioxidant capacity in popular antioxidant-rich US foods. J Food Composition Analysis. 2011;24(7):1043-8.

  35. Rodriguez DB. Quantitative analysis, in vitro assessment of bioavailability and antioxidant activity of food carotenoids. A review. J Food Composition Analysis. 2010;23(7):726-40.

  36. Blasa M, Gennari L, Angelino D, Ninfali P. Fruit and vegetables antioxidants in health. In: Watson R, Preedy V, editors. Bioactive foods in promoting health fruits and vegetables. Arizona USA: Elsevier; 2010. p. 37-58.

  37. Loizzo MR, Tundis R, Bonesi M, Menichini F, Mastellone V, Avallone L, et al. Radical scavenging, antioxidant and metal chelating activities of Annona cherimola Mill. (cherimoya) peel and pulp in relation to their total phenolic and total flavonoid contents. J Food Composition Analysis. 2012;25(2):179-84.

  38. Djeridane A, Yousfi M, Nadjemi B, Boutassouna D, Stocker P, Vidal N. Antioxidant activity of some Algerian medicinal plants extracts containing phenolic compounds. Food Chemistry. 2006;97(4):654-60.

  39. Balasundram N, Sundram K, Samman S. Phenolic compounds in plants and agriindustrial by-products: Antioxidant activity, occurrence, and potential uses. Food Chemistry. 2006;99:191-203.

  40. Bandara V, Weinstein SA, White J, Eddleston M. A review of the natural history, toxinology, diagnosis and clinical management of Nerium oleander (common oleander) and Thevetia peruviana (yellow oleander) poisoning. Toxicon. 2010;56(3):273-81.

  41. Pessoa CR, Riet-Correa F, Medeiros RT, Simões SV, Rapini A. Poisoning by Marsdenia hilariana and Marsdenia megalantha (Apocynaceae) in ruminants. Toxicon. 2011;58(6-7):610-3.

  42. Favilla M, Macchia L, Gallo A, Altomare C. Toxicity assessment of metabolites of fungal biocontrol agents using two different (Artemia salina and Daphnia magna) invertebrate bioassays. Food Chemical Toxicology. 2006;44(11):1922-31.

  43. Nunes B, Carvalho F, Guilhermino LM, Stappen GV. Review: Use of the genus Artemia in ecotoxicity testing. Environmental Pollution. 2006;144(2):453-62.

  44. González AM, Presa M, Latorre MG, Lurá MC. Detección de metabolitos fúngicos con actividad tóxica mediante bioensayo sobre Artemia salina. Rev Iberoamericana Micología. 2007;24(1):59-61.

  45. Santos P, Pinto GB, Takahashi JA, Silva LG, Boaventura MA. Biological screening of Annonaceous Brazilian medicinal plants using Artemia salina (Brine Shrimp Test). Phytomedicine. 2003:10(2-3):209-12.

  46. Hosni K, Jemli M, Dziri S, M'rabet Y, Ennigrou A, Sghaier A, et al. Changes in phytochemical, antimicrobial and free radical scavenging activities of the Peruvian pepper tree (Schinus molle L.) as influenced by fruit maturation. Industrial Crops Products. 2011;34(3):1622-8.




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