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2013, Number 5

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Rev Med Inst Mex Seguro Soc 2013; 51 (5)

Relationship among anthropometric and gluco-metabolic parameters, bone mineral density and endometriosis

Nava-González EJ, de la Garza-Casas YE, Salazar-Montalvo RG, Gallegos- Cabriales EC

Language: Spanish
References: 31
Page: 522-531
PDF size: 402.17 Kb.


ABSTRACT

Background: women with endometriosis may have a decreased bone mineral density (BMD). Several studies have shown that accumulation of adipose tissue profoundly affects BMD. It has also been documented that excess body fat is associated with risk of developing endometriosis. The aim was to analyze the relationship between BMD, fat mass, and the insulin-glucose axis in women with endometriosis.
Methods: thirty women with the diagnosis of endometriosis established by surgery were enrolled to participate in an observational prospective study. Anthropometry was performed to determine body mass index, and a dual X-ray densitometry to collect data on body composition and BMD. Glucose and insulin determinations were performed. Women were divided in two groups: with normal weight (n = 18) or overweight (n = 12). For the analysis of the results, we used descriptive statistics and Pearson test.
Results: normal weight/overweight: mean age 32.5/35.2 years; body mass index 21.5/30.2; adiposity index: 27.7 %/36.1 %; fat mass index: 35.4/45.8 %; women with overweight showed a signifi cant value with p‹ 0.05.
Conclusions: women with overweight, high values of adiposity index and fat mass index were related with endometriosis. The importance could support the hypothesis about a common pathogenesis among endometriosis, osteoporosis, diabetes and obesity.


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