Aisa ÁA, Rosas CM, Reza OM, Díaz GE, Rodríguez WFL

Language: Spanish
References: 61
Page: 137-144
PDF size: 136.07 Kb.

ABSTRACT

Osteoporosis is a disease which is characterized by bone fragility secondary of a low bone mineral density, this leads to an increased risk of fracture. The OMS defines it as a bone mineral density decreasing of -2.5 standard deviations. As Osteoporosis is a multidisciplinary disease that encompasses internist’s population and should be suspected, addressed and treated in a timely manner. Bisphosphonates are drugs that have shown a significant increase in bone mineral density with a high impact in vertebral and hip fractures prevention. These previously mentioned drugs are the most prescribed in internal medicine consultation and are considered the first-line treatment for osteoporosis. Currently the drugs most commonly employed are alendronate, risedronate, ibandronate and zoledronic acid. Lately it has been informed that some rare but serious complications such as osteonecrosis of the jaw, esophageal cancer and atypical femoral fractures. Therefore there is a high controversy about their use.

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