2012, Number 1
<< Back Next >>
Rev Mex Neuroci 2012; 13 (1)
Diagnosis and prognosis of transient ischemic attack in a program of immediate attention
Infante-Valenzuela A, Góngora-Rivera F, Villarreal-Velázquez HJ
Language: Spanish
References: 20
Page: 22-29
PDF size: 218.86 Kb.
ABSTRACT
Introduction: Transient ischemic attack (TIA) is a
syndrome characterized by focal neurologic deficit of
vascular origin, self-limited in ‹ 24 h. Identifying the
etiology and establishing opportune secondary
prevention management diminish the risk of recurrence
and of definite cerebral infarction.
Objective: To describe
the experience in diagnosis, management and
prognosis of acute cerebrovascular syndromes in a
system of immediate clinical attention, the SOS-AIT-HU
program.
Material and methods: In the first year of
operations a total of 83 adults with clinical suspicion of TIA,
referred from the Emergencyand Ambulatory Care
Departments. ICT etiology was classified according to
TOAST and A-S-C-O systems, and stratified according
to ABCD2 and ABCD3+i. All patients received followup
at 30 and 90 days.
Results: A total of 49 (59%) cases
not corresponding genuinely to TIA were identified,
mainly metabolic and convulsive causes. A total of 34
(41%) cases were confirmed with TIA, with etiology
according with TOAST as follows: 7 (20%) large-artery
atherothrombosis, 5 (14%) cardioembolism, 15 (44%)
small-vessel disease, 4 (12%) with other determined
causes and 3 (9%) undetermined. The mean duration
of hospital stay was 2.5 days and in 90% of patients
the etiology was determined in ‹ 3 days. Eleven (35%)
subjects had a lesion in DWI-MRI (minor infarction with
spontaneous recovery ad integrum). Recurrence rate
was 5% and 14% at 30 and 90 days, respectively.
Conclusions: The SOS-AIT-HU program has increased
the registering of patients with TIA and has defined
better the mimicking cases. It has been reached a
similar outcome compared with that of the
international literature. As far as we know, the SOS-AITHU
program is the first of its kind in Mexico.
REFERENCES
Easton JD, Saver JL, Albers GW, Alberts MJ, Chaturvedi S, Feldmann E, Hatsukami TS, et al. American Heart Association; American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; Interdisciplinary Council on Peripheral Vascular Disease. Definition and evaluation of transient ischemic attack: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; and the Interdisciplinary Council on Peripheral Vascular Disease. The American Academy of Neurology affirms the value of this statement as an educational tool for neurologists. Stroke 2009; 40: 2276-93.
Giles MF, Rothwell PM. Risk of stroke early after transient ischaemic attack: a systematic review and meta-analysis. Lancet Neurol 2007; 6: 1063-72.
Wasserman J, Perry J, Dowlatshahi D, Stotts G, Stiell I, Sutherland J, Symington C, et al. Stratified, urgent care for transient ischemic attack results in low stroke rates. Stroke 2010; 41: 2601-5.
Lavallee PC, Meseguer E, Abboud H, Cabrejo L, Olivot JM, Simon O, Mazighi M, et al. A transient ischaemic attack clinic with round the clock access (SOS-TIA); feasibility and effects. Lancet Neurology 2007; 11: 953-60.
Rothwell PM, Giles MF, Chandratheva A, Marquardt L, Geraghty O, Redgrave JN, Lovelock CE, et al. Early use of Existing Preventive Strategies for Stroke (EXPRESS) study. Effect of Urgent treatment of transient ischaemic attack and minor stroke on early recurrent stroke (EXPRESS study) a prospective population based sequential comparison. Lancet 2007; 20(370): 1432-42.
Luengo-Fernandez R, Gray AM, Rothwell PM. Effect of urgent treatment for transient ischaemic attack and minor stroke on disability and hospital costs (EXPRESS study): a prospective population-based sequential comparison. Lancet Neurol 2009; 8: 235-43.
Asimos AW, Johnson AM, Rosamond WD, Price MF, Rose KM, Catellier D, Murphy CV, et al. A multicenter evaluation of the ABCD2 score’s accuracy for predicting early ischemic stroke in admitted patients with transient ischemic attack. Ann Emerg Med 2010; 55: 201-10.
Tsivgoulis G, Stamboulis E, Sharma VK, Heliopoulos I, Voumvourakis K, Teoh HL, Patousi A, et al. Multicenter external validation of the ABCD2 score in triaging TIA patients. Neurology 2010; 74: 1351-7.
Sheehan OC, Merwick A, Kelly LA, Hannon N, Marnane M, Kyne L, McCormack PM, et al. Diagnostic usefulness of the ABCD2 score to distinguish transient ischemic attack and minor ischemic stroke from noncerebrovascular events: the North Dublin TIA Study. Stroke 2009; 40: 3449-54.
Johnston SC, Rothwell PM, Nguyen-Huynh MN, Giles MF, Elkins JS, Bernstein AL, et al. Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack. Lancet 2007; 369: 283-92.
Merwick A, Albers GW, Amarenco P, Arsava EM, Ay H, Calvet D, Coutts SB, et al. Addition of brain and carotid imaging to the ABCD score to identify patients at early risk of stroke after transient ischaemic attack: a multicentre observational study. Lancet Neurol 2010; 9: 1060-9.
Giles MF, Albers GW, Amarenco P, Arsava EM, Asimos AW, Ay H, Calvet D, et al. Early stroke risk and ABCD2 score performance in tissue vs time-defined TIA: a multicenter study. Neurology 2011; 77: 1222-8.
Amarenco P, Bogousslavsky J, Caplan LR, Donnan GA, Hennerici MG. New approach to stroke subtyping the A-S-C-O (phenotypic) classification of stroke. Cerebrovasc Dis 2009: 27; 502-8.
Imray CH, Tiivas CA. Are some strokes preventable? The potential role of transcranial Doppler in transient ischaemic attacks of carotid origin. Lancet Neurol 2005; 4: 580-6.
Rothwell PM, Buchan A, Johnston SC. Recent advances in management of transient ischaemic attacks and minor ischaemic strokes. Lancet Neurol 2006; 5: 323-31.
Sheehan Kyne L, Kelly LA, Hannon N, Marnane M, Merwick A, McCormack PM, Duggan J, et al. Population-based study of ABCD2 score, carotid stenosis, and atrial fibrillation for early stroke prediction after transient ischemic attack: the North Dublin TIA study. Stroke 2010; 41: 844-50.
Giles MF, Rothwell PM. Risk of Stroke early after Transient ischaemic Attack: a systematic review and meta-analysis. Lancet Neurology 2007; 12: 1063-72.
Candratheva A, Mehta Z, Geraghty OC, Marquardt L, Rothwell PM. Oxford Vascular Study. Population-based study of risk and predictors of stroke in the first few hours after a TIA. Neurology 2009; 72: 1941-7.
Yang J, Fu JH, Chen XY, Chen YK, Leung TW, Mok V, Soo Y, Wong KS. Validation of the ABCD2 score to identify the patients with high risk of late stroke after a transient ischemic attack or minor ischemic stroke. Stroke 2010; 41: 1298-300.
Ferrari J, Knoflach M, Kiechl S, Willeit J, Schnabl S, Seyfang L, Lang W. Austrian Strok Unit Registry Collaborators. Early clinical worsening in patients with TIA or minor stroke: the Austrian Stroke Unit Registry. Neurology 2010; 74: 136-41.