Flores AD, Jacobo NS, Álvarez GM, Macedo TE, Colin NJJS

Language: Spanish
References: 24
Page: 195-201
PDF size: 947.28 Kb.

ABSTRACT

Currently, the assisted reproductive technologies had proved to be an appropriate option for patients with infertility. As physicians, it is important having a standardized and analytical protocol study that will allows us to choose the most appropriate and specific treatment. First level studies help us to dismiss the most common diagnosis, such as anatomical dysfunctions, hormone-related pathologies or infectious diseases. If these initial studies do not provide a diagnosis, we have to perform more specific studies to search for immunological disorders and thrombophilias. We submit the case of a patient, GPA 3-2-1 (2 C-section), with secondary infertility and a background history of four cycles of in vitro fertilization (IVF) carried out in two assisted reproduction clinics, with no successful results. It was observed in every cycle a good ovarian response; the patient had 10 embryos transferred in total (with an average of 2-3 embryos per transference) the quality of each embryo was 1+ and 2+. The levels of human chorionic gonadotropin hormone (HCG) were negative in all cycles. When the patient came to our hospital, it was confirmed the normality in all the first level studies that were performed to her and due to the fact of the history of implantation failure, we performed the immunological studies and searched for thrombophillias, finding antinuclear antibodies and antiphospholipids antibodies, with positive levels. We prescribed a medical treatment for three months allowing, at the end of this treatment, two cycles of unprotected sexual intercourses. Our patient attended with six weeks of amenorrhea; we corroborated an intrauterine pregnancy and started with regular prenatal control. Giving birth to a female, gestational age 39 weeks, weight of 2,495 g and APGAR 9/9.

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