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Academia Mexicana de Neurología, A.C.

2010, Number 2

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Rev Mex Neuroci 2010; 11 (2)

Paraneoplas ic neurologic syndrome (Par t I) : Approach and main features

Cacho DB

Language: Spanish
References: 112
Page: 150-159
PDF size: 122.97 Kb.


ABSTRACT

Paraneoplasic neurological syndromes (PNSx) are uncommon diseases with neurological clinical features, which usually precede the diagnosis of cancer. They have heterogeneous clinical presentations involving the central nervous system (CNS) and peripheral (PNS) and/or autonomic nervous system (ANS). PNSx are categorized as classical and non classic presentations, they are sometimes associated with certain antibodies (anti-onconeurals), and the search for an underlying malignancy should be mandatory. Diagnosis is suspected clinically and is confirmed by through certain paraclinical studies and the presence of a PNSx becomes irrefutable when the malignancy is detected. The knowledge of PNSx has a great relevance for the physician, being the most important concern the early diagnosis of the PNSx in order to identify the underlying malignancy to improve the patient prognosis by prescribing the appropriate management.


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