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Academia Mexicana de Neurología, A.C.

2011, Number 2

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Rev Mex Neuroci 2011; 12 (2)

Predictive factors associated to functional disability and death at 30 days in patients with acute ischemic stroke: Results from the RENAMEVASC Study

Murillo-Bonilla LM, Lizola-Hernández J, Lepe-Cameros L, Ruiz-Sandoval JL, Chiquete E, León-Jiménez C, Arauz A, Villarreal-Careaga J, Rangel-Guerra R, Barinagarrementería F, Cantú-Brito C

Language: Spanish
References: 14
Page: 68-75
PDF size: 195.65 Kb.


ABSTRACT

Background: Cerebrovascular diseases are the second cause of death worldwide and 85% of deaths occurred in developing countries as Mexico. Objective: To determine the predictive factors associated to short-term poor outcome or death in patients with acute ischemic stroke in Mexico. Patients and methods: From the RENAMEVASC registry (by the Spanish eponym: REgistro NAcional Mexicano de Enfermedad VAScular Cerebral), we analyzed 891 patients with acute ischemic stroke requiring hospital care. Patients were classified as cases (n367) when clinical outcome at 30 days showed a Rankin score of 4-6 (severe disability or death) and as Controls (n = 524) when they had a Rankin score of 0-3 (good outcome). Demographics, clinical, radiographic, and hospital complications variables were compared between both groups. Results: Case fatality rate was 19.6% and severe disability was observed in 21.5% of cases. Variables that were associated to poor outcome or death included: hemispheric infarction (OR 14.4; p ‹ 0.001), medical hospital complications [cardiac arrhythmia (OR 12.7; p = 0.03) and pneumonia (4.6; p = 0.001)], and admission to a unit care (OR 4.6; p = 0.002). Conclusions: Forty percent of patients in this Mexican population had poor outcome because severe disability or death, being the main associated factors the extension of cerebral infarction and the presence of medical complications.


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