2008, Number 6
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Rev Mex Neuroci 2008; 9 (6)
Correlation between Video-Electroencephalography and Magnetic Resonance Image findings in patients with refractory focal epilepsy
Alarcón-Avilés T, Plascencia-Álvarez NI, Núñez-Orozco L
Language: Spanish
References: 25
Page: 432-437
PDF size: 133.58 Kb.
ABSTRACT
Introduction: Video-electroencephalogram (VEEG) and Magnetic resonance image (MRI) are very important in the evaluation of patients with refractory epilepsy.
Objectives: To establish the relation between the interictal and ictal VEEG findings and the focal structural lesions in the MRI of patients with refractory epilepsy.
Material and methods: We analyze 38 patients (n = 38) with focal epilepsy between 15 and 57 years with prolonged VEEG and MRI, applying central tendency and comparative concordance formula.
Results: 19/38 (50%) had a temporal focus, 16/38 (42.1%) a frontal focus. The most common finding in the MRI was mesial temporal sclerosis (34.21%), encephalomalacia (21.05%), tumors (10.52%). We found a VEEG sensitivity of 0.94 and specificity of 0.84 for temporal lobe focus (Positive Predictive Value, PPV, of 0.91, Negative Predictive Value, NPV, of 0.89), sensitivity for frontal lobe was 0.79 and specificity 0.84 (PPV 0.80, NPV 0.78). The Kappa value was 0.78 for temporal lobe focus and 0.78 for frontal lobe focus.
Conclusion: When we find focal alterations in the VEEG is necessary to search structural lesions with MRI because the possibility of finding a lesion is very high (84.21% in our sample).
REFERENCES
Hauser WA, Kurland LT. The epidemiology of epilepsy in Rochester, Minnesota, 1935 through 1967. Epilepsia 1975; 16: 1-66.
Sander JW, Shorvon SD. Epidemiology of the epilepsies. J Neurol Neurosurg Psychiatry 1996; 61: 433-43.
García-Pedroza F, Rubio-Donnadieu F, García-Ramos G, Escobedo- Ríos F, González-Cortés A. Prevalence of Epilepsy in Children: Tlalpan, Mexico City, Mexico. Neuroepidemiology 1983; 2: 16-23.
Guidelines for epidemiologic studies on epilepsy. Commission on Epidemiology and Prognosis, International League Against Epilepsy. Epilepsia 1993; 34: 592-6.
Remy S, Beck H. Molecular and cellular mechanisms of pharmacoresistance in epilepsy. Brain 2006; 129(1): 18-35.
Cohen I, Navarro V, Clemenceau S, Baulac M, Miles R. On the origin of interictal activity in human temporal lobe epilepsy in vitro. Science 2002; 298: 1418-21.
Fisher RS, van Emde Boas W, Blume W, et al. Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE). Epilepsia 2005; 46: 470-2.
Núñez-Orozco L, Plascencia-Álvarez N, Malagón-Valdez J. Epilepsia. Una perspectiva clínica. México: Editorial Prado; 2007.
WHO. Atlas: Epilepsy care in the world 2005. Program for Neurological Diseases and Neuroscience. Department of Mental Health and Substance Abuse. Geneva: World Health Organization; 2005, p. 1-96.
Camfield P, Camfield C. Long-term prognosis for symptomatic secondarily generalized epilepsies: a population-based study. Epilepsia 2007; 48: 1128-32.
Devinsky O, Kelley K, Porter RJ, et al. Clinical and electrographic features of simple partial seizures. Neurology 1988; 18: 1347-52.
Boon P, Calliauw L, De Reuck J, et al. Clinical and neurophysiological correlations in patients with refractory partial epilepsy and intracranial structural lesions. Acta Neurochir Wien 1994; 128: 68-83.
Ghougassian DF, d’ Souza W, Cook MJ, et al. Evaluating the utility of inpatient video-EEG monitoring. Epilepsia 2004; 45: 928-32.
American Electroencephalographic Society. Guideline twelve: Guidelines for long-term monitoring for epilepsy. J Clin Neurophysiol 1994; 11: 88-110.
Cascino GD. Video-EEG monitoring in adults. Epilepsia 2002; 43: 80-93.
Tatum WO. Long term video-EEG monitoring. A clinical approach to electrophysiology. J Clin Neurophysiol 2001; 18: 442-5.
Schreiner A, Pohlmann-Eden B. Value of the early electroencephalogram after a first unprovoked seizure. Clin Electroencephalogr 2003; 34: 140-4.
Bare MA, Burnstine TH, Fisher RS, et al. Electroencephalographic changes during simple partial seizures. Epilepsia 1994; 35: 715-20.
Roupakiotis SC, Gatzonis SD, Triantafyllou N, et al. The usefulness of sleep and sleep deprivation as activating methods in electroencephalographic recording: contribution to a long-standing discussion. Seizure 2000; 9: 580-4.
Betting LE, Mory SB. MRI reveals structural abnormalities in patients with idiopathic generalized epilepsy. Neurology 2006; 67: 848-52.
Knake S, Triantafyllou CL, et al. 3T phased array MRI improves the presurgical evaluation in focal epilepsies: A prospective study. Neurology 2005; 65(7): 1026-31.
Asano E, Pawlak C, Shah A, et al. The diagnostic value of initial video-EEG monitoring in children–review of 1000 cases. Epilepsy Res 2005; 66: 129-35.
Provini F, Plazzi G, Tinuper P, et al. Nocturnal frontal lobe epilepsy. A clinical and polygraphic overview of 100 consecutive cases. Brain 1999; 122(Pt 6): 1017-31.
Donat JF. Long-term EEG monitoring for difficult seizure problems. J Child Neurol 1994; 9(Suppl. 1): S57-S63.
Panayiotopoulos CP, Chroni E, Daskalopoulos C, Baker A, Rowlinson S, Walsh P. Typical absence seizures in adults: clinical, EEG, video- EEG findings and diagnostic/syndromic considerations. J Neurol Neurosurg Psychiatry 1992; 55: 1002-8.