2013, Number 06
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MediSan 2013; 17 (06)
Identification of the human papilomavirus in oral leukoplakia
Estrada PGA, Márquez FM, Hernández ÁG, Oliveros Noriega-Roldán S
Language: Spanish
References: 12
Page: 944-950
PDF size: 40.10 Kb.
ABSTRACT
With the purpose of evaluating the results of the clinical and histopathological
diagnosis of the human papilomavirus associated with oral leukoplakia, a
descriptive and cross-sectional study was carried out in 75 patients with this
condition, who were treated at the Stomatology Department of the Polyclinic of
Specialties from "Saturnino Lora" Provincial Teaching Clinical Surgical Hospital of
Santiago de Cuba, from September 2009 to the same month of 2012. Biopsies
were taken from patients to detect the presence of koilocytes producing chorion
and epithelial changes in damaged tissue, as well as their topographic location.
Male sex, buccal mucosa as the anatomical site of highest incidence and epithelial
dysplasia as the most significant prevailed in the case material. Likewise, the loss
of the nuclear-cytoplasmic ratio and hyperplasia of the basal layer were the most
frequent tissue alterations.
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