2013, Number 3
<< Back Next >>
Rev Invest Clin 2013; 65 (3)
Morbidity of breast cancer and cervico-uterine cancer in women from the Occidental region of Mexico
Ortega-Cervantes L, Rojas-García AE, Robledo-Marenco ML, Barrón-Vivanco BS, Girón-Pérez MI, Vallejo-Ruiz V, López-Flores JF, Carrillo-Cortez A, Cantú-De León D, Rodríguez-Trejo A, Medina-Díaz IM
Language: English
References: 20
Page: 221-227
PDF size: 147.65 Kb.
ABSTRACT
Background. The incidences of breast cancer (BC) and cervico-uterine cancer (CC) vary widely from country to country. In Mexico, BC mortality has doubled in the last 20 years to become the second leading cause of death for women aged 30 to 54 years. CC is the most common cause of death from neoplasia in women over 25 years old. In 2006, the state of Nayarit had one of the highest mortality rates for these types of cancers in Mexico.
Objective. To analyze and characterize the current demographics and morbidities associated with BC and CC in the state of Nayarit.
Material and methods. In this retrospective study, the clinical histories of patients who were diagnosed with BC or CC at the State Cancer Center from January 2006 to December 2010 were analyzed.
Results. A total of 406 patients with BC and 328 patients with CC were registered. The most common clinical stage for both cancer types was IIB. The municipalities of San Pedro Lagunillas and El Nayar presented the highest prevalences of BC and CC, respectively.
Conclusion. Our results suggest that women living in poorer and more marginalized regions have a higher possibility of developing BC and CC. Because BC and CC are preventable and treatable in their early stages, demographic information from population records for these cancers is helpful in determining the incidence rates and patterns and improving decision-making processes.
REFERENCES
International Agency for Research on Cancer. Cancer Incidence and Mortality Worldwide (IARC, GLOBOCAN 2008). Lyon: World Health Organization, 2010 [accessed: January, 2012]. Available: http://globocan iarc.fr/
Knaul FM, Nigenda G, Lozano R, et al. Cáncer de mama en México: una prioridad apremiante. Sal Pub Mex 2009; 51(Suppl. 2): 335-44.
Zheng L, Zheng W, Chang B, et al. Joint effect of estrogen receptor β sequence variants and endogenous estrogen exposure on breast cancer risk in Chinese women. Cancer Res 2003; 63: 7624-9.
Tovar-Guzmán V, Hernández-Girón C, Lazcano-Ponce E, et al. Breast cancer in Mexican women: an epidemiological study with cervical cancer control. Rev Saude Publica 2000; 34: 113-9.
Sistema Nacional de Información en Salud. Principales causas de mortalidad en mujeres [accessed: October, 2012]. Available: http://www.sinais.salud.gob.mx
Instituto Nacional de Geografía y Estadística. Censo General de Población y vivienda 2000 [accessed: January, 2010]. Available: http://www inegi.org.mx/sistemas/TabuladosBasicos/Default.aspx?c=16852&s=est
Consejo Nacional de Población. México en cifras proyecciones de la población en México 2005-2014 [accessed: October, 2012]. Available: http://www.conapo.gob.mx/es/CONAPO/Estatales
Organización Mundial de la Salud 2002. La estandarización: Un método para la comparación de tasas. Boletín Epidemiológico [accessed: January, 2012]. Available: http:// www.paho.org/spanish/sha/be_v23n3-estandariz.htm
Frenk J. Sensibilización, detección temprana y combate a los prejuicios Claves en la lucha contra el cáncer de mama. Sal Pub Mex 2009; 51(Suppl. 2): 135-7.
Sosa-Rubí SG, Walker D, Serván E. Práctica de mastografías y pruebas de Papanicolaou entre mujeres de áreas rurales de México. Sal Pub Mex 2009; 51(Suppl. 2): S236-S245.
Escandón-Romero C, Benítez-Martínez MG, Navarrete-Espinoza J, et al. Epidemiología del cáncer cervicouterino en el Instituto Mexicano del Social. Sal Pub Mex 1992; 34: 607-14.
Palacio-Mejía LS, Lazcano-Ponce E, Allen-Leigh B, et al. Diferencias regionales en la mortalidad por cáncer de mama y cérvix en México entre 1979 y 2006. Sal Pub Mex 2009; 51(Suppl. 2): 208-19.
Plan Estatal de Desarrollo 2005-2011 Gobierno del Estado de Nayarit [accessed: May, 2012]. Available: http://www.seplan.gob.mx/des/ped/ped_nay_6_sierra.pdf
González-Arias CA, Robledo-Marenco ML, Medina-Díaz IM, et al. Patrón de Uso y Venta de Plaguicidas en Nayarit, México. Rev Int Contam Ambient 2010; 26: 221-8.
Chen X, Weaver JE, Bove BA, et al. Allelic imbalance in BRCA1 and BRCA2 gene expression is associated with an in creased breast cancer risk. Hum Mol Genet 2008; 17: 1336-48.
Torres-Mejía G, Ángeles-Llerenas A. Factores reproductivos y cáncer de mama: principales hallazgos en América Latina y el mundo. Sal Pub Mex 2009; 51(Suppl. 2): 165-71.
Lozano-Ascencio R, Gómez-Dantés H, Torres-Sánchez L, et al. Tendencias del cáncer de mama en América Latina y El Caribe. Sal Pub Mex 2009; 51(Suppl. 2): 147-56.
American Joint Committee on Cancer. Breast cancer staging. American Cancer Society 7th ed. 2007 [accessed: May, 2012]. Available: http://www.cancerstaging.org/staging/index.html
International Agency for Research on Cancer. Appendix 1. Figo staging of cervical carcinomas [accessed: May, 2012]. Available: http://screeningiarc.fr/viaviliappendix1.php?lang=3
National Comprehensive Cancer Network. NCCN Guidelines Version 3.2012. Invasive Breast Cancer [accessed: Nov, 2012]. Available: http://www.nccn.org/professionals/physician_gls/pdf/cervical.pdf