2012, Number 4
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Rev Cubana Hematol Inmunol Hemoter 2012; 28 (4)
Local application of platelet lysate on posflebitic ulcers
Gámez-Pérez A, Arteaga-Báez JM, Rodríguez-Orta CA, Saavedra-Martínez N, González- Cordero F, Sanabria-Negrín JG, Fernández- Delgado N, Hernández-Ramírez P, Borrego-Rodríguez B, González-Portales Y, Pérez- Mesa DS, Santos-Saavedra Y, Ford Revol D, Semino BB
Language: Spanish
References: 21
Page: 374-384
PDF size: 199.95 Kb.
ABSTRACT
Treatment of post-thrombotic ulcers or postflebitic is a challenge to medicine
because of its chronicity and frequent recurrences that determine multiple local and
systemic disorders with poor quality of life for patients. This study included 80 patients
with lower limb posflebitic ulcers, who were grouped into 2 groups: 40 treated with
preserved allogeneic platelet lysates and 40 were treated conventionally. The latter
was the control group. It was considered good result when the patient had a partial
or complete response after 30 days of treatment or before. Good response was
found in 95 % of patients treated with lysate (sum of total and partial values)
versus 75 % in the control group (p › 0.001). The use of platelet lysate was a
simple and effective procedure in the treatment of lower limb posflebitic ulcers. This
treatment can be recommended, since patients can stay at home, thus eliminating
the hospital costs incurred in this type of treatment.
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