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2013, Number 2

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Rev Cubana Pediatr 2013; 85 (2)

Anomalies of the urinary tract and microorganism other than Escherichia coli in the neonatal urinary infection

Díaz ÁM, Acosta BB, Arango AMI, Pérez CR, Medina GT, Hernández RE

Language: Spanish
References: 26
Page: 180-191
PDF size: 83.19 Kb.


ABSTRACT

Objective: to confirm whether the type of microorganism isolated in newborns with initial urinary tract infection and the anomalies of the urinary tract are associated or not.
Methods: prospective and observational study of a cohort of 427 newborns, who were admitted to the hospital with their first urinary infection in the upper tract based on clinical criteria, and they underwent renal ultrasound and urethrocystography. The relationship between the vesicourethral reflux and other anomalies of the urinary tract with the type of causative microorganism of the urinary tract infection was analyzed.
Results: bacterial isolates in uricultures were Enterobacteriaceae genus microorganisms in 402 patients (94.1 %), led by E. coli in 276 (64.6 %). The prevalence of anomalies of the urinary tract was 23.6 x 100. The most prevalent problem was vesicourethral reflux found in 82 patients (19.2 x 100). It was confirmed that the presence of vesicourethral reflux had statistically significant association, in terms of risk, with causative microorganism other than E. coli (RR: 1.56; p‹ 0.05). Similarly, the presence of vesicourethral reflux or of other type of anomalies in the urinary tract was related to the causative microorganism of the urinary tract infection and the results of the analysis were similar (RR:1.64; p‹ 0.01).
Conclusions: although E. coli is the most frequent causative microorganism of the neonatal urinary tract infection, when an isolate different from E. coli is obtained, it is very likely that the patient carries some anomaly of the urinary tract since the presence of the vesicourethral reflux and other anomalies of the urinary tract are significantly associated to microorganisms other than E. coli.


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