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2005, Number 4

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Rev Endocrinol Nutr 2005; 13 (4)

Nutritional genomic: Perspectives for the future

Pérez CE, Meléndez MG, Zúñiga RA

Language: Spanish
References: 33
Page: 190-196
PDF size: 102.45 Kb.


ABSTRACT

Health and disease processes depend upon the interaction between an individual genetic background and its environmental conditions. The outcome of this relationship creates a unique phenotype in human beings. In this sense, inter-individual genetic diversity explains how nutrients requirements are defined for a particular subject, this is Nutrigenetics; whereas the diet and its active components modify the genetic expression in a constant and dynamic manner to maintain homeostasis according to personal necessities at each stage of life cycle, it’s about Nutrigenomics. Nutrition Genomics is giving birth to these two new areas of science, Nutrigenetics and Nutrigenomics, which supported by new technology, will be able to explain back and forward the interaction of nutrients and genes. The future of Clinical Nutrition also will demand developing new knowledge about proteomics, metabolomics and transcriptomics, aimed to enhance our understanding of a specific diet design. This new paradigm will also require to introduce new concepts about Ethics, Policies and Laws on Nutritional Genetics, with power enough to protect Patients Privacy and avoid manipulation of genetics background of societies or individuals and transforming population recommendations into a more personalized, “genetic tailor made” diet.


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