Maldonado-Silva K, Reyna-Figueroa J, Ortiz-Ibarra FJ, Valenzuela-Méndez E, Limón-Rojas AE

Language: Spanish
References: 18
Page: 75-78
PDF size: 148.28 Kb.

ABSTRACT

A new molecular biology technique was used simultaneously in two patients with systemic inflammatory response syndrome and negative cultures who were given broad-spectrum antibiotics without a vis ble improvement. The first case is a patient of 17 months who was admitted to the Pediatric Intensive Care Unit with a diagnosis of abdominal septic shock. In the last episode had fever and persistent laboratory abnormalities and the cultures were negative on three occasions, SeptiFast was requested as an alternative test with a sample of blood from the catheter in place and identified the genetic material of Candida parapsilosis and Klebsiella pneumoniae/oxytoca, and the catheter was removed, with adequate response from the patient and discharged when the infection was solved.
The second case is a male patient of 16 days of life who was admitted at birth in infants service because of respiratory distress and necrotizing enterocolitis, at 72 hours from the suspension of the antimicrobial treatment started with fever, abdominal distension, leukopenia and thrombocytopenia. New cultures were requested and SeptiFast test with one milliliter of peripheral blood, which identified Candida parapsilosis as the pathogen agent. The treatment was changed to amphotericin B deoxycholate with improvement at 24 hours of the change.

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